Potential Abnormality of Glucose Tolerance, Appetitive Behavior
Conditions
Keywords
blood glucose, emmer bread, glycemic index, glycemic load, blood pressure
Brief summary
This study characterized emmer seeds, flours, and breads, and investigated the effects of emmer breads on the glycemic response
Detailed description
This study aimed to 1. describe the technological characteristics of emmer seeds, flours, and breads, 2. determine the glycemic index and glycemic load of two emmer breads, and 3. to investigate the effects of these breads on postprandial glycemic response in healthy subjects
Interventions
Fourteen healthy, normal weight subjects (male: 6, female: 8) after 10-14 hr fast, consumed 50g glucose diluted in 300ml water, tested three times, in different visits, within 5-10min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90 and 120min.
Fourteen healthy, normal weight subjects (male: 6, female: 8) after 10-14 hr fast, consumed 50g available carbohydrates from Greek emmer bread, tested once, in different visits, within 5-10min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90 and 120min.
Fourteen healthy, normal weight subjects (male: 6, female: 8) after 10-14 hr fast, consumed 50g available carbohydrates from Italian emmer bread, tested once, in different visits, within 5-10min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90 and 120min.
Fourteen healthy, normal weight subjects (male: 6, female: 8) after 10-14 hr fast, consumed 50g available carbohydrates from whole wheat commercial bread, tested once, in different visits, within 5-10min. Fingertip capillary blood glucose samples were taken at baseline, 15, 30, 45, 60, 90 and 120min.
Sponsors
Study design
Masking description
Single (Investigator)
Intervention model description
Crossover Assignment
Eligibility
Inclusion criteria
* healthy * non-smoking * non-diabetic men and women * body mass index (BMI) between 18 and 27 kg/m2
Exclusion criteria
* severe chronic disease (e.g. coronary heart disease, diabetes mellitus,kidney or liver conditions, endocrine conditions) * gastrointestinal disorders * pregnancy * lactation * competitive sports * alcohol * drug dependency
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Capillary blood glucose responses | 2 hours | Clinically useful change in blood glucose, defined as the restoration of glucose within normal limits during the 2hr glucose tolerance test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subjective appetite ratings | 2 hours | Useful change in subjective appetite using visual analogue scales with a score 0 to 10 (given in the form of booklet,one scale per page) at baseline, 15, 30, 45, 60, 90 and 120 min. The minimum or maximum score will be evaluated if it is better or worse depending on the appetite variable e.g hunger, satiety, desire to eat etc. |
| Blood pressure | 2 hours | Useful change in systolic and diastolic blood pressure before and 2hr after consumption of the breads |
Countries
Greece