Open Trial of Telehealth Group for Improving Peer Relationships (PEERS) in NF1

Effectiveness of a Telehealth Group for Improving Peer Relationships for Adolescents With Neurofibromatosis Type 1

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04856514

Enrollment

Registered

2021-04-23

Start date

2020-12-05

Completion date

2021-07-31

Last updated

2021-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurofibromatosis 1, Social Skills

Brief summary

This is an open trial of the UCLA PEERS protocol delivered via Telehealth with teens with neurofibromatosis type 1 whose parents report that they have difficulty making and keeping friends.

Interventions

BEHAVIORALPEERS

16 week telehealth intervention; parallel teen and parent/caregiver groups; 90 minutes each week.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

12 Years to 17 Years

Healthy volunteers

Yes

Inclusion criteria

* Physician diagnosis of neurofibromatosis type 1 * Age 12-17 * Main language spoken in the home is English * Reliable internet access * Current functional impairment in peer relationships * Teen is interested and motivated to participate

Exclusion criteria

* Main language spoken in the home is not English * Cognitive or developmental delays that affect reading comprehension or understanding of treatment material * Significant behavioral concerns * Other comorbid medical conditions * Major surgery in past 6 months * Prior social skills group treatment within past 6 months * Prior participation in PEERS

Design outcomes

Primary

Measure	Time frame	Description
Social Skills Improvement System - SEL (SSIS-SEL; Gresham & Elliot, 2017)	within four weeks of PEERS completion	Parental report of social skills (SSIS-SEL Total Score; Mean 100, SD 15; Higher scores mean stronger social functioning
Test of Adolescent Social SKills (TASSK: Laugeson & Frankel, 2010)	within four weeks of PEERS completion	Questionnaire completed by teen participants; measures knowledge of the PEERS intervention concepts (raw total score; higher score means stronger functioning)

Secondary

Measure	Time frame	Description
Social Responsiveness Scale (SRS; Constantino, 2005)	within four weeks of PEERS completion	Questionnaire completed by caregivers on social function and autism symptoms (SRS Total Score; Mean 50, SD 10; higher scores mean greater difficulties

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026