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Comparison of Thoracic Paravertebral Block and Pectoral Nerve Block

Comparison of the Results of Ultrasound-Guided Thoracic Paravertebral Block and Modified Pectoral Nerve Block for Postoperative Analgesia in Video-Assisted Thoracoscopic Surgery; A Prospective, Randomized Controlled Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04855994
Enrollment
52
Registered
2021-04-22
Start date
2017-06-28
Completion date
2018-08-28
Last updated
2021-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Analgesia, Thoracic Paravertebral Block, Video-assisted Thoracoscopic Surgery

Keywords

Thoracic paravertebral block,, pectoralis block,, Video-assisted thoracoscopic surgery,, Postoperative analgesia

Brief summary

This study aims to compare the efficacy and safety of ultrasound-guidedPECS II block with TPVB for postoperative analgesia after VATS.

Detailed description

52 patients (ASA I-III) between 18 and 65 years of age, who were to undergo VATS, were randomized and divided into two groups. (26 patients in each of the PECS and TPVB groups) Thoracic paravertebral block was administered from two consecutive levels for TPVB group and a modified pectoral nerve block was performed in the PECS group. Postoperative analgesia was provided by intravenous morphine infusion using a patient-controlled analgesia device. Postoperative 24-hour total morphine consumption and duration of analgesia were the primary outcome measure. Perioperative remifentanil use, visual analog scale values during at rest and coughing, time of the first analgesic request, and additional analgesic consumption were recorded.

Interventions

PROCEDUREparavertebral block

The investigators performed Paravertebral block to that patient group for postoperative analgesia

The investigators performed pectoral block to that patient group for postoperative analgesia

Sponsors

Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Ages of 18-65 * Patients who will undergo VATS * ASA I-II-III patients

Exclusion criteria

* Patients with ASA IV * Clinically diagnosis of spinal or chest wall deformity or pathology * Clinically known local anesthetic allergy * Morbid obesity (body mass index\>40 kg m2) * Clinically diagnosis of opioid, alcohol and substance dependence * Clinically diagnosis of psychiatric disease * Coagulopathy

Design outcomes

Primary

MeasureTime frameDescription
Postoperative 24-hours total morphine consumption of patients24 hours postoperativelyThis will be measured only one time by pca device at the 24th hour after surgery.

Secondary

MeasureTime frameDescription
Visual Analog Scale values of patients24 hours postoperativelyVisual Analog Scale (VAS, 0-10; 0= no pain and 10= very severe unbearable pain) at 0-1-2-4-8-12 and 24th hours

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026