Premenstrual Syndrome
Conditions
Keywords
whole body vibration, aerobic exercises, premenstrual syndrome
Brief summary
The purpose of this study is to investigate and compare the effect of whole-body vibration to aerobic exercise on inflammatory status in females with premenstrual syndrome.
Detailed description
Premenstrual syndrome (PMS) is a complex disorder characterized by moderate to severe symptoms taking place during the luteal phase of the menstrual cycle. It has a negative impact on females' lives, which can affect their relationships, educational efficiency, social activities, and quality of life. Despite previous studies reported that physical exercise improves the symptoms of PMS, the effects of physical exercise on inflammatory status in females with PMS are not clear yet. sixty females allocated to three groups randomly to group (A) that will receive whole-body vibration+supplementation, group (B) that will receive aerobic exercises+supplementation, and group c that will receive supplementation only
Interventions
OTHERwhole body vibration
All participants in the WBV group will perform the WBV training on a vibrating device (Confidence Vibration Plate Power Plus, China), which produces a lateral peak-to-peak oscillation. They will stand on the WBV platform with a 150° knee angle during the exposure minute. They started the training with three sets of 1 min separated by a 1-min resting period and vibration amplitude of 1 mm. They will add one set every session until they performed 10 sets of WBV. The frequency started at 20 Hz, which will be increased gradually by 2 Hz every 2 weeks +magnesium (Mg) (250 g) and vitamin B6 supplementation
OTHERaerobic exercise
the subjects will receive aerobic exercises+ magnesium (Mg) (250 g) and vitamin B6 supplementation
OTHERsupplementation
the subjects will receive magnesium (Mg) (250 g) and vitamin B6 supplementation
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
random generator
Intervention model description
whole-body vibration and aerobic exercise
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 25 Years
Healthy volunteers
No
Inclusion criteria
1. Females suffering from PMS (as determined by PMS scale). 2. Their ages will range from 18 to 25 years. 3. Having regular menstrual cycle.
Exclusion criteria
1. Smoking. 2. Taking any medications. 3. History of chronic disease. 4. Having any psychiatric or gynecological problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| premenstrual symptoms | up to twelve weeks | The premenstrual syndrome questionnaire also measured the occurrence and severity of two menstrual pain symptoms, including cramp and backache experienced during the first 2 days of the women' last menstrual period. Premenstrual symptoms were scaled as: mild (1); moderate (2); and severe (3). Young women with PMS should experience a premenstrual symptoms score of at least 50% greater than the postmenstrual score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| CRP level assessment | up to twelve weeks | blood sampl a normal reading is less than 10 milligram per liter (mg/L), more than 10 milligram the level of inflammation in body increase. |
| cortisol level | up to twelve weeks | When a technician carries out the cortisol level test between 6 a.m. and 8 a.m., the results will typically be within the range of 10-20 micrograms per deciliter (mcg/dL). more than 20 the level of stress increased. |
| hormonal analysis | up to twelve weeks | blood sample will be used for assessment the level of progesterone and prolactin. normal level of progesterone less than 0.20 ng/mL and Normal levels of prolactin in females: less than 25 ng/mL |
Countries
Egypt
Outcome results
None listed