Microcornea Within One Year of Age
Conditions
Brief summary
This subject is mainly to study difference of Congenital cataract preoperative related parameters in children with or without Microcornea within Less than one year old. A total of 186 eyes of 117 people were collected with relevant ocular biological parameters, including age, horizontal diameter of the cornea, Eye axis, intraocular pressure, steep axis of corneal curvature, flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth. At present, because the definition of patients with small cornea is not clear enough, the study subjects are divided into 4 groups according to the horizontal corneal diameter of 9.0mm, 9.5mm, and 10.0mm, namely ≤9.0mm group, 9\ 9.5mm group, 9.5\ 10.0mm group and The \>10.0mm group compares the differences between each other, and tries to provide a reference for the diagnosis of children with small cornea at a young age.
Interventions
DEVICECollect ocular biological parameters including age, corneal diameter, eye axis, intraocular pressure, steep&flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth
observation
Sponsors
Wenzhou Medical University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Months to 12 Months
Healthy volunteers
No
Inclusion criteria
* Congenital cataract children with or without Microcornea within Less than one year old * Complete collection of eye biological parameters before the first-stage Congenital cataract surgery * The nutritional status and development of the included subjects have no obvious defects
Exclusion criteria
* congenital persistent pupilary membrane * lens sublaxation or lens dislocotion * Marfan syndrome * Down's Syndrome * Peters abnormality * Fevr * history of obvious eye trauma * obvious macula * long-term (local or systemic) use of glucocorticoids.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| horizontal diameter of the cornea | 2015.5.1-2020.12.1 | Use a ruler to measure during surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| corneal thickness | 2015.5.1-2020.12.1 | Handheld corneal thickness measuring instrument |
| lens thickness | 2015.5.1-2020.12.1 | A-type ultrasonic measuring instrument |
| anterior chamber depth | 2015.5.1-2020.12.1 | SS-OCT |
| flat axis of corneal curvature | 2015.5.1-2020.12.1 | Handheld eye curvature measuring instrument |
| Eye axis | 2015.5.1-2020.12.1 | A-type ultrasonic measuring instrument |
| intraocular pressure | 2015.5.1-2020.12.1 | i care handheld tonometer |
| steep axis of corneal curvature | 2015.5.1-2020.12.1 | Handheld eye curvature measuring instrument |
| age | 2015.5.1-2020.12.1 | — |
Countries
China
Outcome results
None listed