Vestibular Schwannoma
Conditions
Brief summary
MR Fingerprinting (MRF) will be performed in patients who will be treated with Gamma Knife radio surgery for a vestibular schwannoma before the intervention. Fifty patients will be included with a vestibular schwannoma of minimum 1cm in size. During follow-up, response of the tumor to radiosurgery will be evaluated for each patient with MRI. The aim of the study is to find patterns of vestibular schwannomas in MRF data which correlate with the type of response to radio surgery, i.e. tumor control after radiosurgery, further tumor growth despite radiosurgery, cystic transformation after radiosurgery.
Interventions
OTHERMR Fingerprinting
Specific Magnetic Resonance Imaging protocol
Sponsors
Medical University of Vienna
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Inclusion criteria
Planned Gamma Knife radiosurgery for vestibular schwannoma of minimum 1cm in size -
Exclusion criteria
Vestibular Schwannoma of less than 1cm in size. Other a priori treatment than Gamma Knife radiosurgery \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tumor control | 3 years | Number of patients without further growth of the tumor on follow-up MRI after radiosurgery |
| Tumor growth | 3 years | Number of patients with growth of the tumor on follow-up MRI after radiosurgery |
| Cystic transformation | 3 years | Number of patients with cystic transformation of the tumor on follow-up MRI after radiosurgery |
Countries
Austria
Contacts
Primary ContactDorian Hirschmann, MD
Backup ContactJosa Frischer, MD
Outcome results
None listed