Speech-based Digital Biomarker for Psychiatric Disease

Preclinical Development of a Speech-based Digital Biomarker for Psychiatric Disease

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04851912

Enrollment

200

Registered

2021-04-21

Start date

2021-04-27

Completion date

2023-12-31

Last updated

2022-09-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Language, Psychiatric Disorder, Speech

Brief summary

The general objectives of this study are to build a proof-of-concept, speech-based, digital biomarker for identifying the presence and tracking the severity of psychiatric disease.

Detailed description

The purpose of this study is to gather longitudinal data to examine how speech features and symptoms change over different intervals of time and the reliability of repeated, high frequency test administration. Participants will complete a variety of speech and language tasks using the Winterlight Assessment (iOS app) everyday for 30 days. The following is the list of assessments that participants will complete; 1) Daily assessment of mood, 2) Winterlight assessment which contains a series of verbal response tasks where participants are recorded through a tablet app, and 3) Clinical assessments.

Interventions

OTHERWinterlight Apps

Longitudinal speech recordings

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 95 Years

Healthy volunteers

Yes

Inclusion criteria

* Male and Female adults aged 18 to 95. * English as a first language, or English as a second language with conversational proficiency. * Own an iOS device (iPhone or iPad) and willing to install the study app. * A reliable (cellular or WiFi) home internet connection and accessible email address

Exclusion criteria

* Residence outside of Canada or the United States. * Clinically significant vision impairment (corrected vision is acceptable). * Clinically significant hearing impairment (use of hearing aids is acceptable)

Design outcomes

Primary

Measure	Time frame	Description
Speech recordings	Everyday for 30 business days until study completion, about 2 years	500+ features to be extracted from each recording

Secondary

Measure	Time frame	Description
Depression scores	Everyday for 30 business days until study completion, about 2 years	Depression and depression like scores to be collected through surveys

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026