Sarcopenia
Conditions
Brief summary
The overall aim of the proposed project is to improve muscle strength in older adults with possible sarcopenia by promoting home-based progressive resistance exercise. The target population for health talks is community-dwelling older adults. A Three monthly home-visits and weekly phone calls will be made. A waitlist randomised controlled trial will be conducted to evaluate effectiveness, and qualitative feedback will be collected from participants. A pilot study will be conducted first.
Interventions
BEHAVIORALExercise
The intervention is to be taught by fitness trainer at the participants' home at the start of each phase. The exercise progression model for older adults recommended by the American College of Sports Medicine, which emphasise gradual increments in training load and systematically alter one or more programme components, will be adopted.
Sponsors
The University of Hong Kong
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
65 Years to 89 Years
Healthy volunteers
Yes
Inclusion criteria
The inclusion criteria are: * Aged 65-89; * Possible sarcopenia (defined by AWGS 2019); * No cognitive impairment (Abbreviated Mental Test score ≥8); and * No communication problems. The
Exclusion criteria
are: * having engaged in a structured exercise programme in the past 6 months or planning to do so within the intervention period; * mobility-limiting injury of the hands or lower limbs, surgery or hospitalisation within the intervention period; * contraindications such as musculoskeletal/cardiorespiratory disorders, or any advanced diseases that inhibit them from exercising.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in lower-limb muscle strength at 12 weeks from baseline | 12 weeks after baseline | Measured by Short Physical Performance Battery (SPPB), higher score indicates better performance |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in lower-limb muscle strength at 24 weeks from baseline | 24 weeks after baseline | Measured by Short Physical Performance Battery (SPPB), higher score indicates better performance |
Other
| Measure | Time frame | Description |
|---|---|---|
| Status of possible sarcopenia at 24 weeks from baseline | 24 weeks after baseline | Indicated by 5-time chair stand test ≥12 second, or men and women with \<28 kg and \<18 kg strength |
| Change in handgrip strength at 12 weeks from baseline | 12 weeks after baseline | Measured by a spring-type dynamometer, higher value indicates better performance |
| Change in handgrip strength at 24 weeks from baseline | 24 weeks after baseline | Measured by a spring-type dynamometer, higher value indicates better performance |
| Sarcopenia risk score at 24weeks from baseline | 24 weeks after baseline | Measured by SARC-CalF, which is a combination of SARC-F questionnaire and calf circumference, a cut of of \>=11 indicates high risk |
| Sarcopenia risk score at 12 weeks from baseline | 12 weeks after baseline | Measured by SARC-CalF, which is a combination of SARC-F questionnaire and calf circumference, a cut of of \>=11 indicates high risk |
| Status of possible sarcopenia at 12 weeks from baseline | 12 weeks after baseline | Indicated by 5-time chair stand test ≥12 second, or men and women with \<28 kg and \<18 kg strength |
Countries
Hong Kong
Outcome results
None listed