Dynamic Arterial Elastance to Predict Postural Change Induced Hypotension

Investigation on Dynamic Arterial Elastance as a Predictor of Hypotension Caused by the Positional Change From Supine to Prone (SuProne Study).

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04850092

Enrollment

Registered

2021-04-20

Start date

2021-12-15

Completion date

2022-07-15

Last updated

2022-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension

Brief summary

During general anesthesia, hypotension might occur during positional change. It is reported that hypotension after positional change from supine to prone is mainly caused by the decrease in preload. The investigators aimed to investigate whether dynamic arterial elastance might predict hypotension associated with positional change from supine to prone.

Interventions

OTHERPositional change from supine to prone

Patient is turned from supine to prone position for spine surgery

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients planned for invasive arterial catheter insertion, undergoing elective spine surgery in prone position under general anesthesia

Exclusion criteria

* arrythmia * pulmonary disease * increased intracranial pressure * decreased cardiac function (ejection fraction \< 50%) * obesity (body mass index \> 40)

Design outcomes

Primary

Measure	Time frame	Description
Dynamic arterial elastance before positional change	1 minute before positional change	Dynamic arterial elastance, defined as the ratio of pulse pressure variance/stroke volume variance will be recorded 1 minute before positional change

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026