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Diagnostic Performance of Point of Care Ultrasound to Identify Intestinal Obstruction

Diagnostic Performance of Point of Care Ultrasound to Identify Intestinal Obstruction

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04848415
Acronym
OCCLUS
Enrollment
150
Registered
2021-04-19
Start date
2021-05-01
Completion date
2022-09-01
Last updated
2026-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowel Obstruction

Keywords

Bowel obstruction, Computed tomography, Ultrasound

Brief summary

As reported in previous studies, Point-of-Care Ultrasound (POCUS) has good performance for the diagnosis of bowel obstruction even when compared with CT. This inexpensive, radiation-free tool is available in a majority of ED. It is performed at the patient's bedside with immediate results. The learning curve allows Emergency Physicians (EP) to perform this exam after a relative brief training period. The investigators aim to investigate the ability of POCUS performed before CT to exclude the diagnosis of bowel obstruction in patients admitted for abdominal pain.

Detailed description

Bowel obstruction (BO) is frequently suspected in the Emergency Department (ED). Computed Tomography (CT) is commonly used to diagnose this disease. However, CT is not always available in real-time, requires technician times, is associated with increased cost and exposes patients to radiations. The researchers will investigate the diagnosis performances of POCUS for the diagnosis of BO with comparison with CT which will be considered as the gold standard. The wain objective will be the ability to exclude the diagnosis of BO, the main criteria being the negative predictive value. The secondary objectives will be the diagnosis performances (sensitivity, specificity, positive predictive value), duration and difficulty of POCUS

Interventions

OTHERPoint-of-Care Ultrasound

Patients admitted to the ED with abdominal pain and suspicion of bowel obstruction : realization of a Point-of-Care Ultrasound after clinical exam by the Emergency Physician in charge as a standard of care. Beside usual findings, the investigators will search for signs of bowel obstruction: dilated and incompressible small bowel loop, back-and-forth peristalsis sign. Determination of probability of small bowel obstruction. Realization of a computed tomography in search of small bowel obstruction.

Sponsors

Nantes University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

: * Adult patients * Abdominal pain * Suspected bowel obstruction

Exclusion criteria

: \- Documented end-of-life precluding CT realization

Design outcomes

Primary

MeasureTime frameDescription
Negative predictive value of POCUSThrough ED stay, up to 24 hoursNegative predictive value of POCUS for the diagnosis of bowel obstruction compared with computed tomography result

Secondary

MeasureTime frameDescription
Positive predictive value of POCUS for the diagnosis of bowel obstructionThrough ED stay, up to 24 hoursPositive predictive value
Sensitivity of POCUS for the diagnosis of bowel obstructionThrough ED stay, up to 24 hourssensitivity of POCUS, for the diagnosis of bowel obstruction compared with computed tomography result
Specificity of POCUS for the diagnosis of bowel obstructionThrough ED stay, up to 24 hoursspecificity of POCUS, for the diagnosis of bowel obstruction compared with computed tomography result

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 26, 2026