Skip to content

Effect of Honey and Dexamethason on Extraction Healing

A Novel Therapeutic Approach for Controlling Complications Associated With Impacted Mandibular Third Molar Removal

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04848259
Enrollment
80
Registered
2021-04-19
Start date
2021-01-05
Completion date
2021-06-27
Last updated
2021-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impacted Third Molar Tooth

Brief summary

Natural honey and dexamethason will be given before impaction removal then postoperative complications will be evaluated

Detailed description

Patient with impacted lower third molar will be selected to this study agording to agent applied preoperative. Group 1 will receive topical honey and Group 2 will receive IV dexamethason. After surgical removal of impacted tooth under local anesthesia postoperative pain mouth opening, and swelling will be evaluated

Interventions

DRUGNormal saline

Saline will be applied after surgery

DRUGDexamethasone

Dexamethason will be given IV before surgery

DRUGHoney

Honey will be applied locally after surgery

DRUGDexamethasone and honey

Dexamethason will be given IV before surgery and then Honey will be applied locally after surgery

Sponsors

Al-Azhar University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* impacted 3rd molar * healthy patient No smoking

Exclusion criteria

* history of smoking Medical disease

Design outcomes

Primary

MeasureTime frameDescription
Interincisal distancePreoperativeDistance between upper and lower teeth will be measured in mm by ruler
EdemaPreoperativeMeasured from angle of mandible to angle of mouth

Countries

Saudi Arabia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026