Diet, Food and Nutrition, Glycemic Control
Conditions
Brief summary
The specific goal of this pilot study is to evaluate if it is possible to detect a statistical difference in postprandial glycemia after meals served with and without a drink previously shown to reduce postprandial glycemia by about 25%. A third drink, with a new recipe, is also included for comparisons. Six participants will carry continuous blood glucose monitors for 10 days and follow a specific meal schedule. The data from this study will form the basis for forming hypothesis of future studies as well as make appropriate calculations of statistical power.
Interventions
DIETARY_SUPPLEMENTDrinks containing 5AA+CrPic and Placebo
Same diet will be repeated for 3 days in a row and the beverage switched every day. 3 periods of 3 days are included in the study.
Sponsors
starScience GmbH
DoubleGood AB
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI 25-29.9 kg/m\^2 * HOMA-IR \< 2.5 * Fasting glucose \< 6.1 mmol/L * Stable weight since 3 months * Access to iPhone with Bluetooth 4.0 and iOS 13 or later
Exclusion criteria
* Diabetes * Pharmacological treatment known to interfer with metabolism * Antibiotics treatment the latest 3 months * Vegetarian/Vegan diet * Use of tobacco * Pregnancy or breast-feeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postprandial glucose response | From start of meal (0 min) to 120 min postprandially | Incremental area under the blood glucose curve after each meal |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Glycemic variability | 24 hour cycles | Variation in blood glucose levels |
Countries
Sweden
Outcome results
None listed