Africa, Coronavirus Infection
Conditions
Keywords
Coronavirus infection, SARS-CoV, COVID-19, Transmission, Africa
Brief summary
The purpose of this study is to Understand the natural history of Coronavirus 2019 (COVID-19) infection to better define the period of infectiousness and transmissibility and to establish biobanks of COVID-19 blood and mucosal samples.
Detailed description
In this study ,the participants will be enrolled sequentially in the COVID-19 care referral centers. The infected hospitalized patient will be identified by the physicians in hospital. After the patient has given his/her informed consent the permission will be sought from him to approach his household contacts. The household contacts will be screened, and included in the study. Patients hospitalized and positive for COVID-19 by PCR and their household contacts of all ages and gender (40% minimum of female), will be enrolled upon receipt of written informed consent.
Interventions
None listed
Sponsors
European and Developing Countries Clinical Trials Partnership (EDCTP)
Leiden University Medical Center
Institut de recherche en santé de surveillance épidémiologique et de formation
Université des Sciences de la Santé
Armauer Hansen Research Institute, Ethiopia
Universität Tübingen
Centre de Recherche Médicale de Lambaréné
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Inclusion criteria
* Molecular (PCR) confirmed COVID-19 patients hospitalized in referral centers, * Household contacts of hospitalized COVID-19 patient, * Provided signed informed consent.
Exclusion criteria
* Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical and biological parameters of COVID-19 | 14 days | Infection and disease progression - Pattern of virus transmission |
| SARS-CoV-2 transmissibility | 14 days | proportion of household contact who will become positive for SARS-COV2 using PCR |
Countries
Gabon
Outcome results
None listed