Bile Reflux, Ulcer, Gastric
Conditions
Brief summary
MGB is considered to be the best alternative to Roux-en-Y gastric bypass (RYGB) due to the shorter operation time and fewer possible complications. The purpose of this study was to determine biliary reflux in patients undergoing MGB/OAGB with a hand-sewn gastroenteroanastomosis, and MGB/OAGB with a stapler gastroenteroanastomosis.
Interventions
DIAGNOSTIC_TESTfibrogastroscopy, biopsy of the gastric mucosa, microscopy biopsy materials, using Bile Reflux Index
fibrogastroscopy, biopsy of the gastric mucosa, microscopy biopsy materials, using Bile Reflux Index
Sponsors
Private Healthcare Institution Clinical Hospital RGD-Medicine
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* morbid obesity * BMI above 35 kg/m2 with obesity related comorbidity * BMI above 40 kg/m2 * undergoing MGB/OAGB * no bile reflux during preoperative period
Exclusion criteria
* revisional operations * therapy-resistant bile reflux during preoperative period * history of bariatric surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Success | 12 month | Determination of the BRI index in patients undergoing MGB/OAGB can be used as a screening method for diagnosing biliary reflux in order to prevent and develop tactic for further management of patients from a risk group of complications associated with the toxic effects of an aggressive bile |
Countries
Russia
Contacts
Primary ContactArut Mezhunts
Outcome results
None listed