Idiopathic Purpura Fulminans Associated With Anti-PS Antibodies in Children

Idiopathic Purpura Fulminans Associated With Anti-PS Antibodies in Children: a French Multicenter Retrospective Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04845113

Enrollment

200

Registered

2021-04-14

Start date

2021-01-01

Completion date

2021-07-31

Last updated

2021-10-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Purpura

Keywords

Protein S acquired deficiency, Idiopathic purpura fulminans

Brief summary

Idiopathic purpura fulminans by anti-protein S antibody is a very rare but potentially extremely serious entity. The data in the literature are poor with only isolated report boxes and a single series of less than 10 boxes. The creation of a larger series of cases would make it possible to better understand this pathology and to offer assistance in diagnosis and management.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 18 Years

Healthy volunteers

Inclusion criteria

* diagnostic of idiopathic purpura fulminans * Acquired protein S deficiency

Exclusion criteria

\- Other infecious purpura diagnosis

Design outcomes

Primary

Measure	Time frame	Description
Rate of anti-protein S antibody	1 day	Rate of anti-protein S antibody

Countries

France

Outcome results