Impact of Regional Anesthesia on Blood Pressure in Lower Limb Traumatism

Impact of Regional Anesthesia on Blood Pressure in Lower Limb Traumatism : IRB (Impact of Regional Anesthesia on Blood Pressure)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04844372

Acronym

IRB

Enrollment

250

Registered

2021-04-14

Start date

2021-03-01

Completion date

2022-03-29

Last updated

2022-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture, Ankle, Fracture Leg

Keywords

Surgery for Ankle and/or leg fracture

Brief summary

This study aims to compare the hemodynamic impact of two anaesthetic strategies 'Regional anesthesia' versus 'General anesthesia' in leg and ankle fractures surgery.

Detailed description

Leg and/or ankle surgery is frequently performed under General Anesthesia (GA). GA is frequently associated with a high risk of hypotension with significant consequences. Regional anesthesia could be an interesting alternative to GA in order to limit hemodynamic consequences, especially in elderly patients. Furthermore, in the current state of Covid 19 crisis, regional anesthesia could provide solutions in preserving drugs for GA and exposing less medical staff on patient's airway. Currently, unlike neuraxial anesthesia, few data deal with impact of peripheral RA and hemodynamic consequences. The investigators hypothesize that the use of Regional anesthesia reduces the use of intraoperative vasopressor. After ethical committee approval, a retrospective cohort of patients with lower limb traumatism, in Montpellier's University Hospital, was analyzed from 2016 to 2020. An informational note was given to all patients participating to the study.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ASA I - IV * Ankle and/or leg fracture * Operated between january 2016 and december 2020 at Montpellier

Exclusion criteria

\- age \< 18 years

Design outcomes

Primary

Measure	Time frame	Description
use of vasopressors	during surgery	use of vasopressors during surgery

Secondary

Measure	Time frame	Description
Total dose of vasoconstrictor	during surgery	Total dose of vasoconstrictor administered
Duration of peroperative hypotension	during surgery	Duration of peroperative hypotension
Post-operative complications	up to 7 days	Nausea/vomiting ; Cardiovascular complications ( dysrhythmias, ischaemia, Complications related to regional anesthesia (sciatic nerve paralysis, femoral) haematoma thromboembolism, sepsis, postoperative cognitive disorders);

Countries

France

Outcome results