Persistent Pulmonary Hypertension of the Newborn
Conditions
Brief summary
Neonatal pulmonary hypertension is a rare but serious condition resulting from a lack of adaptation to extra-uterine life in some newborns. In the short term, the risk of death requires rapid and appropriate management of this transient pathology. In the long term, these newborns present a greater brain vulnerability, a consequence of the pathology itself with cerebral hypoxia but also invasive and aggressive therapies. Although current scientific evidence indicates a correlation with the existence of neurological developmental disorders, the understanding of the long-term neurological outcome of these babies remains poorly documented. Better knowledge of remote neuro-psychomotor development of the critical period
Interventions
OTHERAges & Stages Questionnaires®, Third Edition (ASQ3)
Investigators will propose to parents of children hospitalized for the treatment of persistent pulmonary hypertension of the newborn a hetero-evaluation via the validated ASQ questionnaire to analyze neuro-psychomotor development.
Sponsors
University Hospital, Toulouse
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Years to 5 Years
Healthy volunteers
No
Inclusion criteria
* All parenting authority holders of children aged 1 to 5 years, born after 34 weeks of amenorrhea and having been cared for neonatal PAH in paediatric resuscitation
Exclusion criteria
* Holders of parental authority who cannot answer the questionnaire because they do not speak French. * Opposition of one of the two holders of parental authority * Minor parental authority holders * Holders of parental authority under safeguarding of justice, guardianship or guardianship * Newborns with neonatal PAH with an associated diagnosis of diaphragmatic hernia or cyanogenic congenital heart disease * Newborns with neonatal PAH not treated with nitrogen monoxide
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Describe the association between the occurrence of neuro-psychomotor developmental disorders and initial management in resuscitation. | Between one and 5 years after hospitalization in resuscitation. | Parents will complete ASQ3. The investigators will consider neuro-psychomotor developmental disorders in children with pathological ASQ questionnaire on at least 2 items. |
Countries
France
Outcome results
None listed