Heart Failure, Hospitalization, Life Quality, Morality, Rehabilitation
Conditions
Keywords
cardiac rehabilitation, multidisciplinary program, heart failure, mortality, renin-angiotensin-aldosterone system
Brief summary
This study is looking for the predictors of the survival or rehospitalization of patients with heart failure with reduced ejection fraction. Participants who are discharged from an acute heart failure hospitalization are enrolled.
Detailed description
This study is looking for the predictors of the survival or rehospitalization of patients with heart failure with reduced ejection fraction. Participants who are discharged from an acute heart failure hospitalization are enrolled. The prognostic factors provide information about the treatment of this disease in the future. This study is a retrospective observational study. Investigators will collect data from May 2014 to July 2019 in the heart failure center of Kaohsiung Chang Gung Memorial Hospital. A follow-up is conducted at the Kaohsiung HF center until August 2020. Investigators want to know whether the risk factors such as atrial fibrillation, diabetes, nephropathy, and some biochemical indexes can be an index that predicts future survival or rehospitalization of these patients. Besides, investigators will also explore the cardiac rehabilitation can also effectively improve the survival rate of such patients.
Interventions
OTHERcardiac rehabilitation
multidisciplinary disease management program
Sponsors
Chang Gung Memorial Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Inclusion criteria
* inpatient, age \>= 20 years old, male or female * patient with heart failure with a reduced ejection fraction and discharged alive from the hospital * received heart failure disease management program
Exclusion criteria
* Estimated survival time \< 6 months * Long-term bedridden for more than 3 months * Cannot tolerance exercise test due to muscular-skeletal disorder * Cannot co-operate all functional studies * Ventilator dependent * Terminal heart status * The family reject to participate in this project
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| all-cause mortality | May, 2014 ~ August 2020 | Number of participants that had occurrence of the mortality which is defined as all-cause mortality |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| first heart failure rehospitalization | May, 2014 ~ August 2020 | Number of Participants That Had Occurrence of the Endpoint, Which is Defined as First Heart Failure (HF) Hospitalization |
| Change From Baseline to Month 6 and Month 12 for the Kansas City Cardiomyopathy Questionnaire 12 (KCCQ 12) Clinical Summary Score | May , 2014 ~ August 2020 | Change from baseline to Month 6 and month 12 for the Kansas City Cardiomyopathy Questionnaire short form (KCCQ12) clinical summary score. KCCQ12 is a 12-item, self-administered instrument that quantifies physical function, symptoms (frequency, severity and recent change), social function, self-efficacy and knowledge, and quality of life. KCCQ12 clinical summary score is a composite assessment of physical limitations and total symptom scores. Scores are transformed to a range of 0-100, in which higher scores reflect better health status. |
Outcome results
None listed