Skip to content

Appetite Variability

Appetite Ratings and Eating Patterns

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04836416
Enrollment
109
Registered
2021-04-08
Start date
2021-04-02
Completion date
2022-12-31
Last updated
2024-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appetitive Behavior

Brief summary

This study will examine appetitive sensation variability and the relationship between appetitive sensations and energy intake. Investigators believe the methods for assessing and interpretation of appetitive sensations are problematic and mask the true influence of these sensations on eating. This limits the development of guidelines for weight management. To gain a better understanding of the relationship, investigators will track hourly appetite sensations and map these to eating events via time-series analyses to gain new insights on the directionality and magnitude of these relationships. Also, investigators will also examine the association of apetitive ratings with age or gender. This will allow the development of more effective weight management recommendations.

Detailed description

Screening - The study will be advertised through various public media sources (social media, posted flyers, Purdue Today) and a verbal conversation. Participants responding to the advertisements will be scheduled for a screening visit. This meeting will begin with a full description of the study, and investigators will secure informed written consent. Participants will complete questionnaires eliciting demographic (age, biological sex, BMI, fat%), dietary (eating traits), and health (acute and chronic disease history) information. Height and weight will be measured. For those choosing to enroll, investigators will obtain baseline measurements to confirm eligibility. Individuals qualified and volunteering to participate in the trial will complete multiple questionnaires about eating habits ( Meal pattern questionnaire, Power of food scale, 0 Study Materials - Appetite Training Material.pdf 0 Study Materials - ASA24 instruction .pdf 0 Eating Trait questionnaires.pdf 0 Study Materials - Appetite Lexicon Quiz.docx 0 Hourly Appetite and Thirst Ratings.pdf 0 Study Timeline.pdf Emotional eating scale, Eating inventory, Food craving inventory, Adult eating behavior scales, Self-regulation of eating behavior questionnaire, Barrot Impulsiveness scale). Participants will also learn how to record their energy intake through the ASA-24 system. Then, participants will get training on the lexicon of appetite sensations with a video tutorial, followed by an online quiz to confirm their understanding of the concepts. At least 90% of correct responses are required to pass the appetite lexicon training. Failure to satisfactorily convey an understanding of the concepts will result in an offer to repeat the training two more times or be rejected from the study. Study Procedure - Enrolled participants will have a virtual meeting with a researcher (E. Cheon) once a week through Zoom to remind participants about the necessity and method for recording of appetite/thirst ratings, dietary recalls, and physical activity to be completed during three days (2 non-consecutive weekdays and 1 weekend day). Participants will be asked to report to the laboratory for instruction on recording appetitive sensations (hunger, fullness, thirst), food intake, physical activity at baseline (week1), week 9, and 17 on 3 days (2 non-consecutive weekdays and 1 weekend day). Ratings of hunger, fullness, and thirst will be recorded on their cell phones/computers via a web-based Qualtrics survey every waking hour for 3 days. All entries are time and date stamped to ensure the ratings are made at the intended times. Participants will be provided hourly alarms to ensure regular recording. Concurrently, participants will keep a diet record with an ASA-24 system and free-living energy expenditure will be measured using a physical activity tracking application on the same days of appetite ratings.

Interventions

OTHERObservational

Observational

Sponsors

Purdue University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

1. Age 18-65 years. 2. Body weight fluctuation of \<2.5 kg in the past 3 months.

Exclusion criteria

1. Having an acute disease. 2. Planning to initiate or terminate medication known to affect appetite. 3. Planning to initiate or terminate lifestyle behaviors that could affect energy balance 4. Age \<18 or \>65 years.

Design outcomes

Primary

MeasureTime frameDescription
Gender4 MonthsNo significant association between appetitive sensation intensities and gender.
Hunger4 monthsA positive association between hunger and eating frequency.
Thirst4 MonthsA positive association between thirst and energy intake from beverages.
Fullness4 MonthsA positive association between fullness and portion size.
Energy Intake4 MonthsA positive association between combined hunger (determinant of eating frequency) and fullness (determinant of portion size) ratings and energy intake.
Age4 MonthsA negative association between appetitive sensation intensities and age.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026