Endocrine System Diseases, Gynecomastia
Conditions
Keywords
Prepubertal Gynecomastia, Essential Oils, Lavender, Tea Tree, Endocrine Disruption, Pediatric Environmental Health
Brief summary
The purpose of this study is to explore the potential for an association between the development of prepubertal gynecomastia and history exposure to lavender essential oil, tea tree essential oil, and other essential oils.
Detailed description
After being informed about the study and privacy, parents will give informed consent and complete the APICHS (Aromatic Plant Ingredient & Child Health Survey), a validated measurement tool for determining exposure to plant-based ingredients in pediatric personal care products.
Interventions
OTHERNo Intervention
There is no intervention; observation only.
Sponsors
Nutraceuticals Research Institute
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
2 Years to 15 Years
Inclusion criteria
* Parent of child aged 2-15 living in the United States
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lifetime prevalence of prepubertal gynecomastia | Baseline | The number of participants who were exposed to lavender and tea tree essential oils and had ever experienced prepubertal gynecomastia |
| Lifetime prevalence of precocious puberty | Baseline | The number of participants who were exposed to lavender and tea tree essential oils and experienced prepubertal gynecomastia |
| Endocrine Disruption - Comparison between exposed and unexposed | Baseline | The difference in rates of endocrine disorders between children who were exposed to lavender or tea tree essential oil and those who were not. Exposure is measured using the Aromatic Plant Ingredient and Child Health Survey (APICHS), which measures total exposure, providing a continuous variable ranging from 0 to unlimited exposures, and a dichotomous yes/no exposure outcome variable. |
Countries
United States
Outcome results
None listed