Covid19
Conditions
Keywords
long COVID, post-acute COVID syndrome, persistent symptoms post COVID-19
Brief summary
A large proportion of persons who have had COVID-19 have reported persisted symptoms as fatigue and dyspnea months post infection which affect activities of daily living. The aim of the study is to examine the feasibility and safety of a concentrated rehabilitation program with a mobile application follow-up for persons with persistent symptoms post COVID-19 infection. We will examine recruitment availability, adherence to the program, goal achievement, and resources requirements. Methods: A feasibility study with one group pre-post test design with 10-20 persons between 18-67 years, with persistent symptoms post COVID-19 will be included. The intervention is 3+ 1-2 days concentrated rehabilitation with a mobile application follow-up for 3 months. Following assessments wil be used: Cardiopulmonary exercise testing, lung function, functional performance tests, questionnaires regarding dyspnea, fatigue, anxiety, depression, work-status, health status, sleep behavior, physical activity level. Demographic data before and after the intervention will be presented. Focus group interview will be done with the participants. The interview will be analysed using systematic text condensation.
Detailed description
In March 2020, the World Health Organization (WHO) declared the COVID-19 outbreak to be a pandemic, and a year later more than 120 000 000 people are confirmed with the disease. The disease has caused more than 2 700 000 deaths globally. Norway has a low mortality rate compared to rest of the world. However, a large proportion (10-33%) of the patients worldwide have reported persistent symptoms, such as dyspnea, reduced exercise capacity, loss of taste/smell and fatigue months after the infection. Persistent symptoms are also found in younger populations and in persons with an initially mild disease. The intervention will take place at Helse i Hardanger (HiH)(Health center in Hardanger, Norway). The participants will stay for a 3 -day rehabilitation intervention, if needed, another 1 or 2-day stay will be offered about a month later. The concentrated treatment will be given by an interdisciplinary team, including doctors, physiotherapists, nutritionists, pharmacists, psychologists/psychiatrists, and nurses. The intervention is an individualized group treatment based on behavioural change.
Interventions
OTHERConcentrated rehabilitation for patients with persistent symptoms post COVID-19
3+ 1-2 days concentrated rehabilitation for patients with persistent symptoms post COVID-19 with a mobile application follow-up and physical consultations at 3 months post intervention.
Sponsors
Helse-Bergen HF
Western Norway University of Applied Sciences
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Feasibility study, one group pre-post design
Eligibility
Sex/Gender
ALL
Age
18 Years to 67 Years
Healthy volunteers
No
Inclusion criteria
* persistent symptoms minimum 2 months post COVID-19 infection * reduced exercise capacity level * symptoms of dyspnea and/or fatigue
Exclusion criteria
* diseases where exercise is contraindicated (e.g. unstable angina pectoris) * drug abuse, severe mental illness where treatment in groups are contraindicated.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiopulmonary exercise test (CPET) | 4 months | CPET performed at treadmill |
| Chalder Fatigue Questionnaire (CFQ) | 4 months | Assessing fatigue |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Modified Medical Research Council Dyspnea Scale (mMRC) | 4 months | Assessing dyspnea |
| International Physical Activity Questionnaire (IPAQ) | 4 months | Assessing physical activity |
| Generalized Anxiety Disorder (GAD-7) | 4 months | Evaluation of mental disorders |
| Patient Health Questionnaire (PHQ-9) | 4 months | Assessing health status |
| Bergen Insomnia Scale (BIS) | 4 months | Assessing sleep behavior |
| Client Satisfaction Questionnaire (CSQ-8) | 3 months | Assessing client satisfaction with the treatment |
| Work and Social Adjustment Scale (WSAS) | 4 months | Assessing ability to work and leisure activities. |
| The Brief Illness Perception Questionnaire (BIPQ) | 4 months | Assessing the cognitive and emotional representations of illness. |
| Dyspnea-12 | 4 months | Assessing dyspnea |
| Stair Climbing Test (SCT) | 4 months | Evaluation of functional exercise capacity |
| 30 second sit to stand test (30STST) | 4 months | Evaluation of functional exercise capacity |
| Spirometry, plethysmography and maximal voluntary ventilation | 4 months | Evaluation of lung function |
| Bioimpedance measurement | 4 months | Assessment of body composition |
Countries
Norway
Contacts
Primary ContactBente Frisk, PhD
Backup ContactKiri L Njøten, MSc
Outcome results
None listed