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Board Games Among Mild Cognitive Impairment Patients Experience (GAME Project)

Effectiveness on Cognition of a Cognitive Training Intervention Based on Modern Board and Card Games in Mild Cognitive Impairment Patients: a Randomized Controlled Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04835909
Acronym
GAME-Project
Enrollment
112
Registered
2021-04-08
Start date
2021-02-16
Completion date
2024-03-31
Last updated
2021-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Impairment, Mild

Keywords

Memory, Executive Functions, Cognitive training, Cognitive enrichment, Modern board and card games

Brief summary

Nowadays, on geriatric centres, cognitive decline used to be prevented by pen and paper exercises (Calero García & Navarro Gonzalez, 2006). However, as Lampit et al. (2014) suggest, studies based on the efficacy and effectiveness of new cognitive-based interventions in order to improve these cognitive processes are fundamental (Lampit et al., 2014). Cognitive-based interventions are interventions that directly or indirectly try to improve cognitive processes (Chiu et al., 2017). Between the different kinds of cognitive-based interventions, cognitive training permits stablish randomized controlled trials. Cognitive training consists of repeating during a concrete time a standardized set of tasks in order to maintain or improve one or some cognitive processes. Meta-analysis studies have shown that computerized cognitive training can improve in a moderate size some cognitive processes in elderly people with mild cognitive impairment or dementia (Hill et al., 2017) and without those diagnoses (Lampit, Hallock, & Valenzuela, 2014; Chiu et al., 2017). Although it seems that computerized training is effective, safe and secure, it is important to note the social component of the definition of health (OMS, 1948). Chang, Wray & Lin (2014) found that social relationships predict the use of leisure activities and this predict a better physical health and wellbeing psychological. In fact, a comparative study found that those elderly people that have played board games have a 15% lower risk of having dementia diagnose and problems related with memory (Dartigues et al., 2013). To sum up, the aim of this research project is to test the effectiveness of a cognitive training based on modern board and card games in elderly people with a diagnose of mild-cognitive impairment in comparison to do cognitive paper and pencil tasks or in a wait-list comparison group.

Interventions

BEHAVIORALModern board and card games group

Modern board and card games group

BEHAVIORALPaper and pencil tasks group

Paper and pencil tasks group

Sponsors

University Hospital of Santa Maria, Lleida
CollaboratorUNKNOWN
Brain In Game scientific-technical service
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Participation in cognitive disease center * Amnestic MCI diagnoses (clinical diagnoses following the guidelines of Petersen et al. 2011) * Global deterioration scale (GDS) 2-3 values * Participation assessing outcomes of the caregivers in the study

Exclusion criteria

* Participation in another cognitive training program * Dementia, neurologic or other disease non-neurodegenerative, which could affect cognitive change over time (medical-reported) * Severe visual impairment, language impairment or motoric impairment of the upper extremity which significantly affects ability to solve jigsaw puzzles (medical-reported)

Design outcomes

Primary

MeasureTime frameDescription
Change in phonemic and semantic fluency from baseline to post interventionBaseline and post intervention (after 16 weeks)Animals category and P, M, R letters, Spanish version
Change in verbal working memory from baseline to post interventionBaseline and post intervention (after 16 weeks)Digit Memory Test Backward
Change in visuospatial short-term memory from baseline to post interventionBaseline and post intervention (after 16 weeks)Visual Memory Test Forward
Change in visuospatial working memory from baseline to post interventionBaseline and post intervention (after 16 weeks)Visual Memory Test Backward
Change in visuospatial processing from baseline to post interventionBaseline and post intervention (after 16 weeks)Trail Making Test A and Symbol Digit Modalities Test (SDMT)
Change in flexibility from baseline to post interventionBaseline and post intervention (after 16 weeks)Trail Making Test B and 5 digits test
Change in inhibition from baseline to post interventionBaseline and post intervention (after 16 weeks)5 digits test
Change in cognitive impairment from baseline to post interventionBaseline and post intervention (after 16 weeks)Addenbrooke's Cognitive Examination
Change in visuoconstruction, immediate memory and long-term memory from baseline to post interventionBaseline and post intervention (after 16 weeks)Copy, draw after 3 and after 25 minuts of Rey-Osterrieth Complex Figure Test
Change in verbal long-term memory from baseline to post interventionBaseline and post intervention (after 16 weeks)Rey Auditory Verbal Learning Test (RAVLT)
Change in verbal short-term memory from baseline to post interventionBaseline and post intervention (after 16 weeks)Digit Memory Test Forward

Secondary

MeasureTime frameDescription
Change in neuropsychiatric symptoms from baseline to post interventionBaseline and post intervention (after 16 weeks)Neuropsychiatric Inventory (NPI), Self-reported and caregivers spanish versions. Higher scores mean higher neuropsychiatric symptomatology.
Change in psychological well-being from baseline to post interventionBaseline and post intervention (after 16 weeks)Euro Quality of Life Scale (EQ-5D), Self-reported and caregivers spanish versions. Higher scores mean higher quality of life. Visual analogue scale: minimum value=0, maximum value=100.
Change in depressive symptoms from baseline to post interventionBaseline and post intervention (after 16 weeks)Geriatric Depression Scale (GDS), Spanish version. Higher scores mean higher depressive symptomatology. Minimum value = 0, maximum value = 15.

Other

MeasureTime frameDescription
Cognitive reserve questionnaireBaselineCognitive reserve questionnaire (CRC), spanish version
Premorbid cognitive functionBaselineThe Word Accentuation Test (TAP), spanish version
Social Status Index and sociodemographical informationBaselineHollingshead Index, age, sex, birth location

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026