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Hemodynamic Effect of Prone Position in Non-intubated Patient With COVID 19

Hemodynamic Effect of Prone Positioning in Non-intubated Patient With COVID 19 Pneumonia: a Monocentric Prospective Cohort Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04834947
Enrollment
30
Registered
2021-04-08
Start date
2021-04-15
Completion date
2021-12-15
Last updated
2021-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19, Pneumonia, Viral

Keywords

COVID 19, prone position, hemodynamic effect, spontaneous ventilation

Brief summary

Prone position in non-intubated patient has shown some respiratory physiological benefits. Prone positioning in patient intubated with ARDS has shown hemodynamic benefits. We aim to compare hemodynamic assessment before and after prone positioning in non-intubated patient with COVID 19 pneumonia. The study hypothesis is that prone positioning in non-intubated patient improve right ventricular preload, reduce afterload and increase Cardiac index compared to supine position.

Interventions

PROCEDUREprone position

Choice of prone positioning a patient is at the discretion of the anesthesia physician.

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patient * COVID 19 pneumonias with Hypoxemia * for whom prone positioning has been decided by the attending physician.

Exclusion criteria

* Mechanical ventilation * ECLS

Design outcomes

Primary

MeasureTime frameDescription
Hemodynamic effectCardiac index will be recorded before, just after prone position and after return to supine position.Cardiac index

Countries

France

Contacts

Primary ContactMatthias JACQUET LAGREZE, MD
matthias.jacquet-lagrèze@chu-lyon.fr0033472318933
Backup ContactJean Luc FELLAHI, MD
jean-luc.fellahi@chu-lyon.fr0033472318933

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026