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Artificial Intelligence - SARS-CoV-2 (COVID-19) Risk Evaluation

Artificial Intelligence - SARS-CoV-2 Risk Evaluation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04834934
Acronym
AI-SCoRE
Enrollment
2000
Registered
2021-04-08
Start date
2020-02-16
Completion date
2021-06-30
Last updated
2025-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19

Keywords

Artificial Intelligence, Covid19, Chest CT

Brief summary

The management of COVID-19 patients in overwhelmed hospital facing the pandemic is a clinical challenge. The improvement of decision making may allow a better allocation of available resources and a better treatment of patients at higher risk. Chest CT has been widely adopted for COVID-19 pneumonia diagnosis. Several experiences documented the capability of Artificial Intelligence to improve and fasten COVID-19 pneumonia detection, mainly using chest X-ray. Aim of the present study was to develop and validate an Artificial Intelligence approach integrating clinical and imaging data (automatically extracted through the adoption of dedicated neural networks) for the creation of a cloud platform capable of performing automatic patients risk stratification. Such an approach could be used for triage of COVID-19 patients in the emergency department, with the aim to improve healthcare personnel decision-making and allocation of resources during health emergencies.

Interventions

None listed

Sponsors

Regione Lombardia
CollaboratorOTHER
Orobix Srl
CollaboratorUNKNOWN
Microsoft Corporation
CollaboratorINDUSTRY
ASST Bergamo Est
CollaboratorUNKNOWN
Centro Cardiologico Monzino
CollaboratorOTHER
NVIDIA Corporation
CollaboratorUNKNOWN
PORINI Srl
CollaboratorUNKNOWN
IRCCS San Raffaele
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

* confirmed SARS-CoV-2 infection with RT-PCR * non contrast chest CT scan performed within 72 hours after admission to the emergency department

Exclusion criteria

* age \< 18 ys

Design outcomes

Primary

MeasureTime frame
Training, testing and validation of an AI platform for predicting Italian first wave Covid-19 patients prognosis.9 months

Secondary

MeasureTime frame
Validation of the developed AI platform on italian second wave of Covid-19 patients3 months

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026