Hyaluronic Acid, Corticosteroid and Electrotherapy in Subacromial Impingement Syndrome

Subakromiyal sıkışma Sendromunda Hyaluronik Asit, Kortikosteroid ve Elektroterapi

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04833738

Enrollment

Registered

2021-04-06

Start date

2013-09-11

Completion date

2014-05-28

Last updated

2021-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Shoulder, Subacromial Impingement

Brief summary

Background: Electrotherapy, corticosteroid, and hyaluronic acid have been used to treat subacromial impingement syndrome. However, we need to compare treatment options to provide the optimal results. This study aims to compare the effect of hyaluronic acid, corticosteroid, and electrotherapy in subacromial impingement syndrome. Design: Ninety five patients were randomised into three equal groups according to treatment types. Hyaluronic acid (20 mg/2ml, three times one week apart) or corticosteroid (triamcinolone acetonide, 40 mg/ml, single dose) treatments were applied as subacromial injections. Electrotherapy consisted of 14 sessions TENS (20 min.), hotpack (20 min.) and ultrasound (1.5watt/cm2, 1 MHz, 6 min.). Patients were evaluated before treatment, one and four weeks post end of treatment. Visual Analogue Scale (VAS), range of motion (ROM), and Shoulder Disability Questionnaire (SDQ) were used as outcome measures.

Interventions

DRUGHyaluronic acid

DRUGCorticosteroids Triamcinolone Acetonide

triamcinolone acetonide, 40 mg/ml, single dose

OTHERElectrotherapy

electrotherapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 50 Years

Healthy volunteers

Inclusion criteria

* The diagnosis of subacromial impingement syndrome

Exclusion criteria

* Patients aged \<20 or \>50 years or who have the following medical conditions were excluded: physical therapy or injection in the past 6 months, shoulder instability, acute trauma, adhesive capsulitis, psychiatric illness, diabetes mellitus, malignancy.

Design outcomes

Primary

Measure	Time frame	Description
Visual Analogue Scale	1 min.	Higher scores represent higher level of shoulder pain.
range of motion	5 min.	Higher scores represent lower level of shoulder function.
Shoulder Disability Questionnaire	15 min	Higher scores represent higher level of shoulder pain.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026