Carboxyhemoglobinemia, Fresh Flow
Conditions
Keywords
Low flow anesthesia, Non-invasive carboxyhemoglobinemia monitoring, Smoking
Brief summary
To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level non-invasively and continuous measurement and to determine the contribution of smoking to the intraoperative carbon monoxide accumulation.
Interventions
COHb measurement monitoring from finger pulp with a non-invasive measurement device called Masimo Radical-7 Pulse co-oximeter (Masimo Corporation, Irvine, USA)
Sponsors
Zonguldak Bulent Ecevit University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* ASA I-II * Undergo 2-4 hours of elective surgery
Exclusion criteria
* Cardiovascular disease * diabetes mellitus * kidney, liver failure * chronic obstructive pulmonary disease * patients with opioid sensitivity * morbidly obese * personal or family history of malignant hyperthermia * history of prolonged recovery from anesthesia * alcohol addicted * pregnant and breastfeeding women patients allergic to study drugs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| effects of different fresh gas flows on carboxyhemoglobin levels | during surgery | To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level by non-invasive and continuous measurement. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| effects of smoking on carbon monoxide accumulation. | during surgery | to determine the contribution of smoking to intraoperative carbon monoxide accumulation. |
Countries
Turkey (Türkiye)
Outcome results
None listed