Skip to content

Which is Better Between Single Chest Tube and Multiple Tubes Drainage in Primary Spontaneous Pneumothorax

Comparison of the Efficacy of Single Tube Versus Multiple Tubes Drainage After Bullectomy and Pleurodesis for Primary Spontaneous Pneumothorax

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04831554
Enrollment
200
Registered
2021-04-05
Start date
2021-10-31
Completion date
2023-10-31
Last updated
2021-10-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Spontaneous Pneumothorax

Keywords

number of chest tube, Bullectomy, Pleurodesis, Primary Spontaneous Pneumothorax

Brief summary

There was no evidence that the number of chest tube do effect to the recurrence of pneumothorax, which placed after thoracoscopic wedge resection together with mechanical pleurodesis.This study evaluates the efficacy of single chest tube versus multiple tubes drainage in spontaneous pneumothorax after VATS bullectomy and pleurodesis. After routine procedure the participants will randomized to either placed single chest tube or multiple chest tubes

Detailed description

Primary spontaneous pneumothorax (PSP) occurs after the rupture of small bullae or a subpleural bleb in otherwise normal lungs. The indications for surgical treatment include persistent air leak after intercostal tube drainage, recurrent PSP, and contralateral PSP. The video-assisted thoracoscopic surgery (VATS) approach probably represents the treatment of choice for PSP. The presence of a residual pleural space after surgery may be a factor associated with increased risk of recurrence. One possible hypothesis to explain the association between residual pleural space and recurrence of pneumothorax may be the failed pleurodesis due to lack of pleura-pleura apposition. Multiple chest tubes are effective in clinical practice, but there was no convinctive evidence that the number of chest tube do effect to the recurrence of pneumothorax, which placed after thoracoscopic wedge resection together with mechanical pleurodesis. This study evaluates the efficacy of single chest tube versus multiple tubes drainage in spontaneous pneumothorax after VATS bullectomy and pleurodesis.After routine procedure the participants will randomized to either placed multiple chest tubes or single chest tube. The recurrence of the two group and other postoperative clinical parameters will be observed.

Interventions

PROCEDUREsingle chest tube drainage

place single chest tube after surgery of PSP

Sponsors

Peking University Third Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
16 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosed by chest radiograph or CT as primary spontaneous pneumothorax * Underwent bullectomy and pleurodesis * Postoperative indwelling chest tubes

Exclusion criteria

* Secondary pneumothorax, traumatic pneumothorax and iatrogenic pneumothorax * Previous surgery history * People with severe comorbidities

Design outcomes

Primary

MeasureTime frameDescription
recurrence2 years after operationRecurrence of pneumothorax during 2 years follow-up

Secondary

MeasureTime frameDescription
complications30days after operationpost-operation complications,such as air leakage

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026