Comparison of Figure-Of-Eight Suture Perclose ProGlide Suture-Mediated Closure

Comparison of Figure-Of-Eight Suture and Perclose ProGlide Suture-Mediated Closure System in Achieving Hemostasis After a Large Bore Venous Access.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04831008

Enrollment

Registered

2021-04-05

Start date

2020-08-06

Completion date

2022-12-13

Last updated

2023-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Venous Puncture

Keywords

Perclose Device, Figure-of-eight suture

Brief summary

The study proposes to compare specialized closure devices to achieve hemostasis with the Figure-of-eight suture technique.

Detailed description

Procedures where patients requiring large bore venous access will be randomized 1:1 to either the Figure-of-eight suture technique or the Perclose Device to achieve hemostasis.

Interventions

OTHERFigure-of-eight suture

Using the figure-of-eight closure technique when closing access for structural heart therapies.

OTHERPerclose Device

Using the Perclose device when closing access for structural heart therapies.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* All patients who successfully undergo venous large bore access sheath placement for structural heart procedures.

Exclusion criteria

* Patients who do not consent * Minors or those unable to consent

Design outcomes

Primary

Measure	Time frame	Description
Hemostasis Time	Immediate	To assess if an additional device use to achieve hemostasis can be avoided after a large bore venous access
Procedure Time	Immediate	—
Access Site Complication	1 month	—

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026