Status Epilepticus
Conditions
Keywords
status epilepticus, children, phenytoin, levetireacetam
Brief summary
The purpose of studyis to compare the efficacy of phenytoin with levetiracetam for the management of children with status epilepticus.Study performa consists of demographic variables,exclusion criteria,history of epilepsy and efficacy achieved or not.
Detailed description
After getting informed consent 244 children with status epilepticus will be randomly classified into two groups.one group will receive levetireacetam and other group will be given phenytoin and their efficacy will be compared by observing them for breakthrough fits for next 48 hours.
Interventions
DRUGintravenous levetireacetam
phenytoin is considered as control drug in the study
Sponsors
King Edward Medical University
ayesha tariq
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
2 Months to 12 Years
Healthy volunteers
No
Inclusion criteria
* childen of age less than 12 years either gender admitted in pediatric emergency with status epilepticus
Exclusion criteria
* children already taking either of trial drug or failed treatment with either of trial drug.children with comorbid conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| comparison of efficacy of levetireacetam with phenytoin for the management of children with status epilepticus | 48 hours | the intervention will be considered efficacious if child will not have breakthrough fits for 48 hours |
Countries
Pakistan
Contacts
Primary Contactayesha tariq, MBBS
Backup Contactmohammad Haroon Hamid, MBBS,FCPS
Outcome results
None listed