Guillain-Barre Syndrome (GBS)
Conditions
Brief summary
The aim of this retrospective observational single-center cohort study is to gain a deeper understanding regarding the frequency, the clinical and electrophysiologic characteristics (e.g., the diagnostic work up), complications, treatment regimes, and their associations with specific courses of disease and outcomes in adult patients with the suspected or proven diagnosis of GBS.
Detailed description
Guillain Barré Syndrome (GBS) is a rare and life-threatening neurological emergency. The aim of this retrospective study including adult GBS patients from the last 15 years treated at the University Hospital of Basel is to assess data regarding diagnostic workup, treatment, clinical course including complications and outcomes.
Interventions
OTHERdata collection
Retrospective extraction of demographic, clinical, laboratory, and electrophysiological data from the digital medical records
Sponsors
University Hospital, Basel, Switzerland
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* suspected diagnosis of GBS, who have been treated at the University Hospital of Basel from 01.01.2005-28.02.2021
Exclusion criteria
* Patients with documented refusal of the general consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| frequency of GBS | one time retrospective assessment at baseline | frequency of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel) |
| clinical characteristics of GBS | one time retrospective assessment at baseline | clinical characteristics of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel) |
| electrophysiologic characteristics of GBS | one time retrospective assessment at baseline | electrophysiologic characteristics of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel) |
| complications of GBS | one time retrospective assessment at baseline | complications of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel) |
| treatment regimes of GBS | one time retrospective assessment at baseline | treatment regimes of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel) |
| outcomes of GBS | one time retrospective assessment at baseline | treatment regimes of GBS of all consecutive adult patients with the suspected initial diagnosis of GBS (admitted to the University Hospital Basel) |
Countries
Switzerland
Contacts
CONTACTRaoul Sutter, Prof. Dr. med.
CONTACTLisa Hert, Dr. med.
PRINCIPAL_INVESTIGATORRaoul Sutter, Prof. Dr. med.
Clinic for Intensive Care Medicine, University Hospital Basel
Outcome results
None listed