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Development and Validation of Deep Neural Networks for Blinking Identification and Classification

Development and Validation of Deep Neural Networks for Blinking Identification and Classification

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04828187
Enrollment
8
Registered
2021-04-01
Start date
2020-10-01
Completion date
2021-03-25
Last updated
2023-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blinking, Deep Learning

Keywords

deep learning, DeepLabv3+, iris and sclera segmentation, eye blink detection, complete and incomplete blink classification

Brief summary

Primary objective of this study is the development and validation of a system of deep neural networks which automatically detects and classifies blinks as complete or incomplete in image sequences.

Detailed description

This method is based on iris and sclera segmentation in both eyes from the acquired images, using state of the art deep learning encoder-decoder neural architectures (DLED). The sequence of the segmented frames is post-processed to calculate the distance between the eyelids of each eye (palpebral fissure) and the corresponding iris diameter. Theses quantities are temporally filtered and their fraction is subject to adaptive thresholding to identify blinks and determine their type, independently for each eye. The two DLEDs were trained with manually segmented images and the post-process was parameterized using a 4-minute video. After DLED training, the proposed system was tested on 8 different subjects, each one with a 4-10-minute video. Several metrics of blink detection and classification accuracy were calculated against the ground truth, which was generated by 3 independent experts, whose conflicts were resolved by a senior expert. Two independent blink identifications are assumed to be in agreement, if and only if there is sufficient temporal overlapping and the type of blink is the same between the DLED system and the ground truth.

Interventions

DIAGNOSTIC_TESTComparison of the proposed artificial network with the ground truth

Both eyes will be included for each study participant. Participants watched a 4-10-minute video in standard mesopic environmental lighting conditions at 3.5m viewing distance. Simultaneously, all blinking moves will be recorded through a web infrared camera. The proposed system was tested on the 8 different subjects. Several metrics of blink detection and classification accuracy were calculated against the ground truth, which was generated by 3 independent experts, whose conflicts were resolved by a senior expert. Two independent blink identifications are assumed to be in agreement, if and only if there is sufficient temporal overlapping and the type of blink is the same between the DLED system and the ground truth.

Sponsors

University of Thessaly
CollaboratorOTHER
Democritus University of Thrace
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

* Uncorrected Distance Visual Acuity above 6/12

Exclusion criteria

* corneal opacities * age-related macular degeneration * diagnosis of psychiatric diseases * former eyelid surgery

Design outcomes

Primary

MeasureTime frameDescription
Identification of complete and incomplete blinksup to 1 weekComplete and incomplete blinks are defined by the length of palpebral fissure-to-iris diameter ratio
First frame of each blinkup to 1 weekThe frame in which the upper eyelid starts to move down and cover the cornea
Last frame of each blinkup to 1 weekThe frame in which eyelids open fully after a blink

Secondary

MeasureTime frameDescription
Length of palpebral fissure of both eyesup to 1 weekThe distance between the upper eyelid margin and the lower eyelid margin (ie. the vertical dimension of the palpebral fissure),
Iris diameter of both eyesup to 1 weekThe horizontal diameter of the iris (ie. the horizontal white-to white distance)

Countries

Greece

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026