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Effect of BMI on Postoperative Morbidities of Orthopaedic Procedures

The Effect Of BMI On Thirty-day Postoperative Morbidities And Mortality For The Most Common Orthopaedic Procedures

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04827888
Acronym
BMIORTHO
Enrollment
76189
Registered
2021-04-01
Start date
2012-01-01
Completion date
2020-12-31
Last updated
2021-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Orthopedic Procedures

Keywords

weight, orthopedic surgery, BMI, Post-Op Complication

Brief summary

Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries. Therefore, we aim to determine the effect of BMI on 30-day perioperative outcomes in patients undergoing the first 25 most commonly performed orthopedic surgeries using a retrospective cohort study design. The knowledge of the effect of BMI on orthopedic surgeries will improve the knowledge of surgeons about the expected morbidities.

Detailed description

Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries. Therefore, we aim to determine the procedure specific, independent-effect of BMI on 30-day perioperative outcomes in patients undergoing the first 25 most commonly performed orthopedic surgeries. The study is a retrospective cohort study. The subjects will be the individuals undergoing one of first 25 most commonly performed orthopedic surgeries, whose information is derived form the de-identified patients' data collected through the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. The primary outcome will be composite post-operative morbidity. Specific morbidities will also be evaluated including cardiovascular, vascular and renal complications, length-of-stay (LOS), and the need for re-intervention and readmission, as well as 30-day mortality. Descriptive statistics and multivariable regression models will assess the independent-effect of BMI on outcomes. The knowledge of the effect of BMI on orthopedic surgeries will improve the knowledge of surgeons about the expected morbidities. The surgeon will be able to better counsel obese patients and devise a better surgical plan to prevent or deal with the expected outcomes.

Interventions

PROCEDUREOrthopaedic surgery

One of the 25 most common orthopedic surgeries reported in the database which are the following as per surgical types: spine surgery (CPT codes 63030, 63047, 22612, 22551 or 22558), trauma (CPT codes 27236, 27125, 27244, 27814, or 27792), sports medicine injuries (CPT codes 29881, 29827, 29880, 29888, 29826, 29877, 29807, or 23412), or joint arthroplasty (CPT codes 27447, 27130, 23472, 27487, 27134, 27446, or 27486).

Sponsors

American University of Beirut Medical Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* The inclusion and

Exclusion criteria

are the same as that of ACS-NSQIP database. * All patients who have undergone any of the 25 most common orthopedic procedures as primary procedure as identified through the CPT codes

Design outcomes

Primary

MeasureTime frameDescription
Composite morbiditywithin the 30 days following the surgeryComposite morbidity is defined as the presence of any of the specific morbidities during the 30-days following surgery as recorded in the ACS-NSQIP database. The odds ratio of composite morbidity for each BMI group will be calculated as compared to normal-weight group.

Secondary

MeasureTime frameDescription
woundwithin the 30 days following the surgeryodds ratio of specific morbidity of surgical wound for each BMI group as compared to normal-weight group
cardiacwithin the 30 days following the surgeryspecific morbidity of cardiac complication for each BMI group as compared to normal-weight group
respiratorywithin the 30 days following the surgeryodds ratio of specific morbidity of respiratory complication
urinarywithin the 30 days following the surgeryodds ratio of specific morbidity of urinary complication for each BMI group as compared to normal-weight group
mortalitywithin the 30 days following the surgeryodds ratio of mortality within the 30-days following the surgery for each BMI group as compared to normal-weight group
thromboembolismwithin the 30 days following the surgeryodds ratio of specific morbidity of thromboembolism for each BMI group as compared to normal-weight group
sepsiswithin the 30 days following the surgeryodds ratio of specific morbidity of sepsis for each BMI group as compared to normal-weight group
bleedingwithin the 30 days following the surgeryodds ratio of bleeding or transfusion need for each BMI group as compared to normal-weight group
Re-opwithin the 30 days following the surgeryodds ratio of need for re-admission/re-operation for each BMI group as compared to normal-weight group
neurologicalwithin the 30 days following the surgeryodds ratio of specific morbidity of neurological (CNS) complication for each BMI group as compared to normal-weight group

Countries

Lebanon

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026