Sarcopenia
Conditions
Keywords
sarcopenia, muscle strength, muscle mass, older people
Brief summary
The main objective of this study is to determine the prevalence of sarcopenia in patients hospitalized in the follow-up care and rehabilitation units of the geriatrics department of the Mulhouse French hospital.
Detailed description
Secondary objectives 1. To assess the performance of the SARC-F questionnaire to screen for sarcopenia ; 2. To describe the characteristics of sarcopenic patients hospitalized in each follow-up care and rehabilitation unit (i.e. day hospital, full hospitalization); 3. To identify predictive factors of sarcopenia; 4. To determine, in the subgroup of patients hospitalized in the conventional follow-up care and rehabilitation unit (i.e. full hospitalization), the evolution of sarcopenia between admission and discharge of the following variables : 1. muscle strength, 2. muscle mass, 3. functional ability, 4. dependency. Conduct of research After receiving the written consent of the study participant, all of the following tests and questionnaires will be performed : * SARC-F questionnaire, * measurement of muscle strengh by a grip test, * measurement of muscle mass by impedancemetry (ASM/size2), * 4-meter walking speed test, * Timed-Up and Go (TUG) test, * ADL (Activities of Daily Living) and IADL (Instrumental Activities of Daily Living) questionnaires. For patients in day hospital care, the study will end upon completion of these tests. For patients hospitalized in the conventional follow-up care and rehabilitation unit (i.e. full hospitalization), a follow-up visit will be scheduled within 72 hours prior to the patient's discharge from the service, or at 3 months of hospitalization. The following tests and questionnaires will be performed during this visit: * measurement of muscle strengh by a grip test, * measurement of muscle mass by impedancemetry, * 4-meter walking speed test, * Timed Up and Go (TUG) test, * ADL and IADL questionnaires.
Interventions
PROCEDUREScreening and diagnostic tests for sarcopenia
All of the following tests and questionnaires will be performed : * SARC-F questionnaire, * measurement of muscle strengh by a grip test, * measurement of muscle mass by impedancemetry (ASM/size2), * 4-meter walking speed test, * Timed-Up and Go (TUG) test, * ADL (Activities of Daily Living) and IADL (Instrumental Activities of Daily Living) questionnaires.
Sponsors
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient 60 years of age or older * Patients hospitalized in the follow-up care and rehabilitation units (i.e. day hospital, full hospitalization) of the geriatrics department of the Mulhouse French hospital * Patient who gave consent to participate in the study * Affiliated or beneficiary of a social security scheme
Exclusion criteria
* Patient admitted for palliative care * Bedridden patient * Patient with major neurocognitive disorders preventing impedancemetry or grip test from being performed, or any other medical condition preventing impedancemtery or grip test from being performed * Patient under legal protection * Patient with an unstable psychiatric disorder * Patient under guardianship or curatorship * Patient already included in the study during a previous hospitalization Secondary
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients with sarcopenia | Enrollment | The diagnosis of sarcopenia will be established according to the 2018 criteria of the European Working Group On Sarcopenia in Older People (EWGSOP2) based on the evaluation of muscle strength and muscle mass. Sarcopenia will be defined by an abnormal value measured by a grip test and confirmed by an abnormal value of the ASM/size2 ratio measured by impedancemetry. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Characteristics of sarcopenic patients hospitalized in each follow-up care and rehabilitation unit (i.e. day hospital, full hospitalization) | Enrollment | — |
| Muscle strength | Hospital discharge assessed up to 3 months | In the subgroup of patients hospitalized in the conventional follow-up care and rehabilitation unit (i.e. full hospitalization), the evolution of muscle strength between admission and discharge will be assessed by a grip test. For patients hospitalized for more than 3 months, the grip test will be performed at 3 months. |
| Muscle mass | Hospital discharge assessed up to 3 months | In the subgroup of patients hospitalized in the conventional follow-up care and rehabilitation unit (i.e. full hospitalization), the evolution of muscle mass between admission and discharge will be assessed by the measurement of the ASM/size2 (impedancemetry) ratio. For patients hospitalized for more than 3 months, the measurement of muscle mass will be performed at 3 months. |
| Sensitivity, specificity, positive and negative predictive value of the SARC-F questionnaire | Enrollment | — |
| Timed-Up and Go test (TUG) | Hospital discharge assessed up to 3 months | In the subgroup of patients hospitalized in the conventional follow-up care and rehabilitation unit (i.e. full hospitalization), the evolution of the value of the TUG test between admission and discharge will be assessed. For patients hospitalized for more than 3 months, the TUG test will be performed at 3 months. |
| ADL (Activities of Daily Living) questionnaire | Hospital discharge assessed up to 3 months | In the subgroup of patients hospitalized in the conventional follow-up care and rehabilitation unit (i.e. full hospitalization), the ADL questionnaire will also be performed at hospital discharge, or at 3 months for patients hospitalized for more than 3 months. |
| IADL (Instrumental Activities of Daily Living) questionnaire | Hospital discharge assessed up to 3 months | In the subgroup of patients hospitalized in the conventional follow-up care and rehabilitation unit (i.e. full hospitalization), the IADL questionnaire will also be performed at hospital discharge, or at 3 months for patients hospitalized for more than 3 months. |
| 4-meter walking speed test | Hospital discharge assessed up to 3 months | In the subgroup of patients hospitalized in the conventional follow-up care and rehabilitation unit (i.e. full hospitalization), the evolution of the value of the 4-meter walking speed test between admission and discharge will be assessed. For patients hospitalized for more than 3 months, the 4-meter walking speed test will be performed at 3 months. |
Countries
France
Outcome results
None listed