Impact of PD1-lymphocytes in Bronchoalveolar Lavage of Patients With Lung Cancer

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04827667

Enrollment

Registered

2021-04-01

Start date

2021-03-18

Completion date

2021-12-31

Last updated

2021-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Brief summary

The aim of this trial is to assess PD1-lymphocytes in bronchoalveolar lavage in patients with lung cancer, ILD and asthma.

Detailed description

In this trial, 20 patients with lung cancer, 10 patients with asthma and 10 patients with interstitial lung disease who have to undergo bronchocospy for medical reasons are enrolled. In each patient, bronchoalveolar lavage is performed to assess PD1-lymphocytes.

Interventions

DIAGNOSTIC_TESTbronchoalveolar lavage

Bronchoalveolar lavage is performed by instillation and suction of saline in the middle lobe during bronchoscopy. Cytological examination and flow cytometry will be performed to assess PD-1lymphoctes.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \>18 years * patients with lung cancer, asthma or ILD and indication for bronchoscopy for medical reasons * Ability to provide informed consent

Exclusion criteria

* acute excacerbation in patients with asthma or ILD * endoluminal tumor growth or penumonia in patients with lung cancer

Design outcomes

Primary

Measure	Time frame
To assess and compare PD1-lmyphocytes in bronchoalveolar lavage in patients with malignant and benign lung diseases to evluate their impact in lung cancer patients	6 months

Countries

Austria

Contacts

Primary ContactDaniela Gompelmann

daniela.gompelmann@meduniwien.ac.at0043 1 40400 47730

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026