Chronic Kidney Disease stage3, Chronic Kidney Disease Stage 3A (Disorder), Chronic Kidney Disease Stage 3B, Chronic Kidney Disease, Stage 3 (Moderate), Diet Habit, Kidney Failure, Chronic
Conditions
Keywords
kidney failure, advanced glycation products, chronic kidney disease
Brief summary
Normal-protein and low-AGE through raw or rare proteins diet versus normal-protein and high-AGE diet in stage IIIa-b renal failure patients
Interventions
BEHAVIORALLow-AGE diet
Low-AGE diet during 24 months
BEHAVIORALHigh-AGE diet
High-AGE diet during 24 months
Sponsors
Centre Hospitalier Saint Joseph Saint Luc de Lyon
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 89 Years
Healthy volunteers
No
Inclusion criteria
* Patients with a grade IIIA-B CKD (GFR with CKD-EPI ≥ 30 mL/min and \< 60mL/min) * Informed consent signed * Aged 18 to 89 years
Exclusion criteria
* Protected adult * Acute renal failure * Patient already on a low-AGE diet (\< 1kU AGE/day) following a dietetic consultation * Current participation in another interventional research
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glomerular Filtration Rate | At 24 months | Glomerular Filtration Rate estimated by the CKD-EPI formula with a blood sample |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Proteinuria | At 24 months | Proteinuria (g/24h) found in the 24-hour urine |
Countries
France
Contacts
Primary ContactFanny Doroszewski
Backup ContactGabrielle Normand, MD
Outcome results
None listed