BCG, COVID-19, Health Care Worker, SARS-CoV-2
Conditions
Brief summary
The present study finds opportunities and justifications, taking into consideration that the nature of professional practice in health needs scientific evidence resulting from systematic and systemic studies to strengthen the basis for the decisions made to have an impact on various levels, from the patient to health management itself. In addition, Cabo Verdean authorities may benefit from new evidence obtained by this study. It intends, in a growing number of health professionals exposed or infected with SARS-CoV-2, in the different health structures of the country, to contribute to substantiate a better perception of the problem and the required solutions. Therefore, assessing the potential risk factors for SARS-CoV-2 infection among healthcare workers will be essential to characterize virus transmission, preventing future infections in them and providing the associated healthcare. Due to the advances and important changes described, questions arise that guide this research and allow us to identify the problem.
Detailed description
The problem is stated in the following starting questions: What conditions and factors are associated with infection and non-infection by SARS-CoV-2 among health professionals working in the three hospitals on the islands of Santiago and São Vicente? Which are they (gender, age group, profession, type of contact, etc.)? Where do the infected HCW typically work (sector)? When and how did the infection occur? What is the prevalence of SARS-CoV-2 antibody in professionals with confirmed SARS-CoV-2 infection and in HCW that thought they were not infected by SARS-CoV-2? How long do anti-SARS-CoV-2 antibodies last? What is the impact of infection on unplanned absenteeism? Which symptoms and complaints (if any) persists after SARS-CoV-2 infection?
Interventions
OTHERQuestionaire
A questionnaire will be administered to all participants to evaluate exposures related to infection at the baseline (enrollement) - Baseline questionnaire. A Follow-up questionnaire to all participants will be done after 3 and 6 months. Capillary blood collection, for diagnosis of anti-SARS-CoV-2 Antibodies by rapid test, will be done at the first interview, for all participants (cases and controls). Collection of peripheral venous blood, for analysis of the presence and duration of anti-SARS-CoV-2 Antibodies (N and S) will be done at the first interview, and after 6 months for all participants (cases and controls).
Sponsors
University of Southern Denmark
Institute of Hygiene and Tropical Medicine, NOVA University, Lisbon, Portugal
National Institute of Public Health of Cape Verde, Praia, Cape Verde
Centro de Investigacao em Saude de Manhica
European and Developing Countries Clinical Trials Partnership (EDCTP)
Bandim Health Project, Bissau, Guinea-Bissau
Universidade de Cabo Verde
Study design
Observational model
OTHER
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Being a healthcare professional working in one of the hospitals where the study will take place * Be aged ≥18 years; * Cases: SARS-CoV-2 infection confirmed by PCR test and/or Rapid Antigen Test; * Control: No evidence and/or record of past infection with SARS-CoV-2.
Exclusion criteria
* Case: Confirmation of diagnosis test for SARS-CoV-2 without indication of specimen collection date. * Control: Suspected SARS-CoV-2 infection.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total number of days absent from work due to COVID-19 | From March 2020 to March 2022 | Absenteeism due to COVID-19 related symptoms |
| Unplanned Absenteeism | 6 months after inclusion | Unplanned absenteeism following SARS-CoV-2 infection |
| Symptomatology after infection by SARS-CoV-2 | 6 months after inclusion | If have or not any symptomes after SARS-CoV-2 infection |
| Presence or absence of anti-SARS-CoV-2 Acs | 6 months after inclusion | Presence or not of anti-SARS-CoV-2 Anti-N and anti-S |
| Duration of anti-SARS-CoV-2 Acs | After infection | Time of duration of anti-SARS-CoV-2 Anti-N and anti-S |
Countries
Cabo Verde
Outcome results
None listed