Ischemic Stroke, Thrombi
Conditions
Brief summary
Nearly 3% of patients with ischaemic stroke (IS) have an isolated occlusion of the anterior or posterior cerebral artery in the acute phase of the disease. In those patients, intravenous thrombolysis (IT) is indicated for 4.5 hours after symptoms onset. Due to a lack of data, mechanical thrombectomy (MT) is not considered as a gold standard to treat IS alone or in addition with IT. Therefore, observational studies are needed to understand the clinical evolution of patients with IS treated with IT and/or MT. The ACAPULCO retrospective observational study aims to highlight potential benefits of MT in those patients to improve their management and to propose targeted therapies in the future.
Interventions
None listed
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 and \< 96 * Clinical signs consistent with acute ischemic stroke * Patients who presented within 6 hours of stroke symptoms onset * Isolated occlusion of the anterior or the posterior artery
Exclusion criteria
* Administration of recanalization treatment before hospital admission
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinico-radiological evolution of IS patients with isolated occlusion of the anterior or posterior cerebral artery. | 90 days | Good Neurological Condition Good neurological outcome (GNO) at 3 months will defined using the modified Rankin Scale (mRS). A normal/near normal outcome after procedure is associated with a mRS Scale score = 0-1 and severe disability/death is associated with a mRS Scale score = 5-6 |
Countries
France
Outcome results
None listed