Development Cellular Models of the Ear and Nose to Study the Mechanisms of Hearing

Development of Cellular Models of the Ear and Nose From Patient Samples to Study the Mechanisms of Hearing

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04823195

Acronym

CMAG

Enrollment

Registered

2021-03-30

Start date

2021-06-15

Completion date

2024-06-15

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hearing Loss, GJB2, Cis Regulation, DFNB1

Brief summary

Development of cells culturesissued from Nose and Ear to study auditory mecanisms. Study of the cis-Modulation of the gene GJB2 for the patients with early presbycusis to identify the genetic cause of hearing loss.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Hearing loss Presbycusis Exostosis

Exclusion criteria

* Genetic hearing loss

Design outcomes

Primary

Measure	Time frame	Description
GJB2 cis regulation	2 years	Culture cell model

Countries

France

Contacts

Primary ContactRémi Marianowski

remi.marianowski@chu-brest.fr02-98-22-33-78

Outcome results