Hematopoietic and Lymphoid Cell Neoplasm, Metastatic Malignant Solid Neoplasm
Conditions
Brief summary
This study collects information about perception of cure among patients with cancer that has spread to other places in the body (metastatic). This study aims to determine patients' perception (knowledge) before starting immunotherapy and if differences exist in understanding of treatment to stimulate or restore the ability of the body's immune (defense) system to fight infection and disease (immunotherapy) based on social and economic factors or on race/ethnicity.
Detailed description
PRIMARY OBJECTIVE: I. To assess the proportion of patients with metastatic cancer who anticipate cure before starting immunotherapy. SECONDARY OBJECTIVES: I. To determine if expectations of cure are associated with quality of life and distress. II. To determine if patients' perceptions differ by gender, age, and ethnicity. OUTLINE: Patients complete surveys over 30 minutes about sociodemographic information and perception of immunotherapy, over 10 minutes about expectations of cure, over 10 minutes about anxiety, over 10 minutes about depression, and over 30 minutes about physical well-being. Patients' medical records are reviewed.
Interventions
Medical records are reviewed
OTHERSurvey Administration
Complete surveys
Sponsors
National Cancer Institute (NCI)
City of Hope Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Eligibility Criteria: 1. Patients must be aged 18 and over 2. Patients sufficiently fluent in English 3. Patients must have a cytologically or pathologically verified diagnosis of cancer 4. Patients must have measurable metastatic disease 5. Patients must be initiating immunotherapy 6. Patients must be undergoing evaluation and treatment at City of Hope Cancer Center
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of patients | Up to 2 years | Will assess the percentage of patients who anticipate cure before starting immunotherapy, scoring a '1' on the Perception of cure tool, and anticipate \>75% chance for a cure. |
| Patient Reported Outcomes Measurement Information System (PROMIS) | Up to 2 years | Descriptive analyses (e.g. frequency statistics) will be used to characterize the sample and to look at the association between Patient Reported Outcomes Measurement Information System (PROMIS) tool score with perception of cure score. |
| Functional Assessment of Cancer Therapy-General (FACT-G) | Up to 2 years | Descriptive analyses (e.g. frequency statistics) will be used to characterize the sample and to look at the association between Functional Assessment of Cancer Therapy-General (FACT-G) overall score with perception of cure score. |
| Perceptions of cure | Up to 2 years | Chi-square analyses will be used to examine perceptions of cure by sociodemographic characteristics: gender (male and female), age (\< 60 and \> 60), and ethnicity (white non-Hispanic, Hispanic, and other). |
Outcome results
None listed