Antibiotic Reaction
Conditions
Keywords
Antibiotic prescribing, questionnaire, Antibiotic resistance, behavior
Brief summary
Antibiotic resistance is a major threat in modern medicine. Overuse of antibiotics is an important driver of antibiotic resistance. However, some authors have shown that up to 50% of antibiotic treatments in critically ill patients are inappropriate, mostly because they are used in patients with non-bacterial infections. In order to improve antibiotic use, several antibiotic stewardship programs have been implemented worldwide. However, only few of them have taken into account the determinants of prescribing behaviors. Yet, these determinants have been shown to play a role among general practitioners of hospital doctors. Nevertheless, none of these factors have been studied among intensivists. The current project represent phase 1 of the study : construction and validation of a questionnaire.
Detailed description
Antibiotic resistance is a major threat in modern medicine. Overuse of antibiotics is an important driver of antibiotic resistance. In critical care setting, antibiotic therapies are widely used due to the high number of patients presenting with sepsis. However, some authors have shown that up to 50% of antibiotic treatments in critically ill patients are inappropriate, mostly because they are used in patients with non-bacterial infections. In order to improve antibiotic use, several antibiotic stewardship programs have been implemented worldwide. However, only few of them have taken into account the determinants of prescribing behaviors. Yet, these determinants have been shown to play a role among general practitioners of hospital doctors. Nevertheless, none of these factors have been studied among intensivists. The study is designed to investigate social, cultural, contextual and personal factors influencing antibiotic prescribing among French intensivists. The design will consist of three phases: * Phase 1: construction and validation of a questionnaire * Phase 2: the questionnaire will be sent to all intensivist, including residents, in France * Phase 3: qualitative study, based on semi-structured interviews. The current project represent phase 1 of the study.
Interventions
OTHERContent Validity
For the validity of built, it is generally advisable to include a ratio of 100 participants for 30 questionnaire items. In order to have a suitable questionnaire, we will limit ourselves to 30 items which will be the size of our questionnaire. It was therefore planned to include 100 participants The selection of experts will be based on experience in this area, knowledge and availability. It will be a rescimant physician and an infectious disease doctor. Each expert will be invited in isolation to comment on the items in the questionnaire
Sponsors
Centre Hospitalier Universitaire de Saint Etienne
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Physicians with predominant intensive care practice * Resident, with a minimum of two-month experience in the intensive care unit
Exclusion criteria
* Refusal to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Content validity | months 18 | Construction and validation of a questionnaire by 2 experts in reanimation and infectiology. This questionnaire will include these items: demographic datas, medical data concerning the use of antibiotics, social data exploring the collective and social components of antibiotic prescription, personal data in search of individual factors, attitude to antibiotic therapy. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Face validity | months 18 | the questionnaire will be sent to all intensivist, including residents, in France |
Other
| Measure | Time frame | Description |
|---|---|---|
| Construct validity | months 18 | qualitative study, based on semi-structured interviews. |
Countries
France
Contacts
Primary ContactGUILLAUME THIERY, MD PHD
Backup ContactAMANDINE BAUDOT, CRA
Outcome results
None listed