Comparison of the TOFscan and the TetraGraph During Recovery of Neuromuscular Function

Comparison of the TOFscan and the TetraGraph During Recovery of Neuromuscular Function : a Pilot Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04816539

Acronym

DECURAR-EMG

Enrollment

Registered

2021-03-25

Start date

2021-04-15

Completion date

2021-04-30

Last updated

2021-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuromuscular Blockade

Brief summary

Assess the values of train-of-four ratios with the TetraGraph and thoses obtained with the TOFscan during recovery of neuromusculat function in surgical patients who have been administred rocuronium. Primary outcome : value of TOFratio with the TetraGraph when TOFratio of TOFscan is greater than or equal to 90% Pilot study : no hypothesis

Interventions

DEVICETetraGraph

Use of two monitoring devices of neuromuscular function during surgery

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* age greater than or equal to 18 years old * patients willing to participate and provide an informed consent * elective surgical procedures, without emergency, administration of rocuronium for neuromuscular blockade, and recovery of complete neuromuscular function at the end of the surgery

Exclusion criteria

* patients with unilateral disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or similar wrist injury * patients with systemic neuromuscular diseases such as myasthenia gravis * renal insufficiency or renal failure * significant liver disease * patients having surgery that would involve prepping the arm into the sterile field * allergy to rocuronium

Design outcomes

Primary

Measure	Time frame	Description
Train-of-four ratios	baseline (J0)	Value of TOFratio with TetraGraph when TOFratio with TOFscan is greater than or equal to 90% (first value of three greater than or equal to 90%)

Secondary

Measure	Time frame	Description
Train-of-four ratios	baseline (J0)	Value of TOFratio with TetraGraph when TOFratio with TOFscan is greater than or equal to 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80% and eventually 100%
Train-of-four count	baseline (J0)	Time to recover one, two, three and four responses from TOFcount with TOFscan and TetraGraph

Countries

France

Contacts

Primary ContactClaude Meistelman

c.meistelman@chru-nancy.fr0383153464

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026