Somatization Disorder
Conditions
Keywords
somatic symptom disorder, Somatic Symptom Scale-China, elderly
Brief summary
With the rapid aging and worsening psychological problems worldwide, the special focus on somatic symptom and other psychological diseases of the older population is needed. However, there is no research comparing the incidence of somatic symptom between elderly and non-elderly, and clinical relevance with somatic symptom is uncertain. The study aims to clarify the prevalence of somatic symptom, depression and anxiety disorders in China, to compare physical and psychological difference between the elderly and non-elderly and to explore risk factors for somatic symptom in the elderly.
Detailed description
With the steadily increasing of life expectancy, the aging people is expected to 2 billion by 2050, which brings the deeper demand on the quality of life improvement. The psychological problems is an important factor affecting the quality of life. As reported, 73.6% of urban residents were with mental sub-health, indicating that psychological problem has grown into inevitable issues in hindering healthy development. The elderly, compared with the non-elderly, have unique social and biological characteristics, so psychological problem of the older population deserves special focus. Literatures have investigated aged people with depression or anxiety disorder, but somatic symptom in elderly have rarely been addressed. Somatic symptom disorder prevalence in elderly in European ranged from 0-13.5%. However, there is no research comparing the incidence of somatic symptom, anxiety and depression between elderly and non-elderly and revealing the prevalence of somatic symptom under Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria. Investigators use Somatic Symptom Scale-China (SSS-CN) questionnaire to assess the presence and severity of the symptoms. Patient Heath Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder Screener (GAD-7) are used to evaluate depression and anxiety disorder respectively. The study aims to clarify the prevalence of somatic symptom, depression and anxiety disorders in China, to compare physical and psychological difference between the elderly and non-elderly and to explore risk factors for somatic symptom in the elderly.
Interventions
DIAGNOSTIC_TESTAssessment of somatic symptom disorder with SSS-CN
SSS-CN questionnaire is used to assess the presence and severity of the somatic symptoms
DIAGNOSTIC_TESTAssessment of depressive symptoms disorder with PHQ-9
PHQ-9 questionnaire is used to assess the presence and severity of the depressive symptoms
DIAGNOSTIC_TESTAssessment of anxiety disorder with GAD-7
GAD-7 questionnaire is used to assess the presence and severity of the anxiety disorder
Sponsors
RenJi Hospital
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
1. voluntary participants and gave written consent to participates the study; 2. undertook SSS-CN questionnaire, PHQ-9 and GAD questionnaires；
Exclusion criteria
1. patients who have lost their self-assessed abilities or refuse to participate ; 2. patient with cancer and central nervous system disease; 3. patients who have been previously confirmed serious mental disorders, mental retardation or dementia.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of Participants With Somatic Symptoms Disorder | Within 24 hours of the questionnaire completion. | The scores of Somatic Symptom Scale-China (SSS-CN) questionnaire were recorded. The score higher than 20 was taken as somatic symptom disorder. Percentage of somatic symptom disorder in elderly and in non-elderly were analyzed. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Number of Participants With Somatic Symptoms Disorder Accompanied With Anxiety | Within 24 hours of the questionnaire completion. | anxiety disorder were assessed by Generalized Anxiety Disorder-7 (GAD-7). The percentage of anxiety disorder among the participants with somatic symptoms disorder were analyzed. |
| Number of Participants With Somatic Symptoms Disorder Accompanied With Depression | Within 24 hours of the questionnaire completion. | Depressive disorder were assessed by Patient Health Questionnaire-9 (PHQ-9). The percentage of depressive disorder among the participants with somatic symptoms disorder were analyzed. |
Countries
China
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Elderly Over 60 years old
Assessment of somatic symptom disorder with SSS-CN: SSS-CN questionnaire is used to assess the presence and severity of the somatic symptoms
Assessment of depressive symptoms disorder with PHQ-9: PHQ-9 questionnaire is used to assess the presence and severity of the depressive symptoms
Assessment of anxiety disorder with GAD-7: GAD-7 questionnaire is used to assess the presence and severity of the anxiety disorder | 6,814 |
| Non-Elderly Under 60 years old
Assessment of somatic symptom disorder with SSS-CN: SSS-CN questionnaire is used to assess the presence and severity of the somatic symptoms
Assessment of depressive symptoms disorder with PHQ-9: PHQ-9 questionnaire is used to assess the presence and severity of the depressive symptoms
Assessment of anxiety disorder with GAD-7: GAD-7 questionnaire is used to assess the presence and severity of the anxiety disorder | 2,206 |
| Total | 9,020 |
Baseline characteristics
| Characteristic | Non-Elderly | Total | Elderly |
|---|---|---|---|
| Age, Customized 18-59 | 2206 Participants | 2206 Participants | 0 Participants |
| Age, Customized ≥60 | 0 Participants | 6814 Participants | 6814 Participants |
| Antipsychotics No | 2198 Participants | 8858 Participants | 6660 Participants |
| Antipsychotics Yes | 8 Participants | 162 Participants | 154 Participants |
| Cardio/Cerebrovascular disease No | 2052 Participants | 6956 Participants | 4904 Participants |
| Cardio/Cerebrovascular disease Yes | 154 Participants | 2064 Participants | 1910 Participants |
| Diabetes mellitus No | 2016 Participants | 7099 Participants | 5083 Participants |
| Diabetes mellitus Yes | 190 Participants | 1921 Participants | 1731 Participants |
| Education College | 859 Participants | 2121 Participants | 1262 Participants |
| Education High school | 617 Participants | 2627 Participants | 2010 Participants |
| Education Master and above | 56 Participants | 101 Participants | 45 Participants |
| Education Middle School and below | 670 Participants | 4151 Participants | 3481 Participants |
| Hypertension No | 1797 Participants | 4990 Participants | 3193 Participants |
| Hypertension Yes | 409 Participants | 4030 Participants | 3621 Participants |
| Marital status Divorced | 23 Participants | 113 Participants | 90 Participants |
| Marital status Married | 1842 Participants | 7710 Participants | 5868 Participants |
| Marital status Never married | 172 Participants | 479 Participants | 307 Participants |
| Marital status Widowed | 165 Participants | 698 Participants | 533 Participants |
| Other disease No | 2177 Participants | 8868 Participants | 6691 Participants |
| Other disease Yes | 29 Participants | 152 Participants | 123 Participants |
| Race and Ethnicity Not Collected | — | 0 Participants | — |
| Region of Enrollment China | 2206 participants | 9020 participants | 6814 participants |
| Sex: Female, Male Female | 693 Participants | 3260 Participants | 2567 Participants |
| Sex: Female, Male Male | 1509 Participants | 5740 Participants | 4231 Participants |
| Surgery No | 2202 Participants | 8941 Participants | 6739 Participants |
| Surgery Yes | 4 Participants | 79 Participants | 75 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 0 / 6,814 | 0 / 2,206 |
| other Total, other adverse events | 0 / 6,814 | 0 / 2,206 |
| serious Total, serious adverse events | 0 / 6,814 | 0 / 2,206 |
Outcome results
Primary
Number of Participants With Somatic Symptoms Disorder
The scores of Somatic Symptom Scale-China (SSS-CN) questionnaire were recorded. The score higher than 20 was taken as somatic symptom disorder. Percentage of somatic symptom disorder in elderly and in non-elderly were analyzed.
Time frame: Within 24 hours of the questionnaire completion.
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Elderly | Number of Participants With Somatic Symptoms Disorder | Yes | 4307 Participants |
| Elderly | Number of Participants With Somatic Symptoms Disorder | No | 2507 Participants |
| Non-Elderly | Number of Participants With Somatic Symptoms Disorder | Yes | 1000 Participants |
| Non-Elderly | Number of Participants With Somatic Symptoms Disorder | No | 1206 Participants |
Other Pre-specified
Number of Participants With Somatic Symptoms Disorder Accompanied With Anxiety
anxiety disorder were assessed by Generalized Anxiety Disorder-7 (GAD-7). The percentage of anxiety disorder among the participants with somatic symptoms disorder were analyzed.
Time frame: Within 24 hours of the questionnaire completion.
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Elderly | Number of Participants With Somatic Symptoms Disorder Accompanied With Anxiety | With anxiety disorder | 709 Participants |
| Elderly | Number of Participants With Somatic Symptoms Disorder Accompanied With Anxiety | Without anxiety disorder | 3598 Participants |
| Non-Elderly | Number of Participants With Somatic Symptoms Disorder Accompanied With Anxiety | With anxiety disorder | 233 Participants |
| Non-Elderly | Number of Participants With Somatic Symptoms Disorder Accompanied With Anxiety | Without anxiety disorder | 767 Participants |
Other Pre-specified
Number of Participants With Somatic Symptoms Disorder Accompanied With Depression
Depressive disorder were assessed by Patient Health Questionnaire-9 (PHQ-9). The percentage of depressive disorder among the participants with somatic symptoms disorder were analyzed.
Time frame: Within 24 hours of the questionnaire completion.
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Elderly | Number of Participants With Somatic Symptoms Disorder Accompanied With Depression | With depressive disorder | 1104 Participants |
| Elderly | Number of Participants With Somatic Symptoms Disorder Accompanied With Depression | Without depressive disorder | 3203 Participants |
| Non-Elderly | Number of Participants With Somatic Symptoms Disorder Accompanied With Depression | With depressive disorder | 306 Participants |
| Non-Elderly | Number of Participants With Somatic Symptoms Disorder Accompanied With Depression | Without depressive disorder | 694 Participants |