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Gastric Volume in Elderly Patients Undergoing Staged Bilateral Total Knee Arthroplasty

Ultrasound Assessment of Gastric Volume in Elderly Patients Undergoing Staged-bilateral Total Knee Arthroplasty After Drinking Carbohydrate-containing Fluids: A Prospective Observational Comparative Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04814706
Enrollment
39
Registered
2021-03-24
Start date
2021-03-30
Completion date
2022-05-31
Last updated
2022-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthritis Knee

Brief summary

In the past, some guidelines advised no oral intake for at least 8 hours before any surgery, However, research has shown risks associated with excessive fasting, such as postoperative insulin resistance, and advantages in shorter fasting protocols, such as reduced postoperative nausea and vomiting. The perioperative fasting guidelines of the European Society of Anaesthesiology focus on preoperative carbohydrates. They hold that it is safe for patients to drink carbohydrate-rich fluids up to 2 hours before elective surgery and that drinking carbohydrate-rich fluids improves subjective well-being, reduces thirst and hunger, and reduces postoperative insulin resistance at an evidence level of 1++. Nevertheless, data on drinking carbohydrate fluids before surgery in elderly patients are limited. Some factors have been known to influence the gastric emptying rate, as for example, old age, pain, and the use of opioid analgesics. In the previous study, evidence of increased pain was reported in patients undergoing staged bilateral total knee arthroplasty, in whom the second operated knee had greater sensitivity (tertiary hyperalgesia) due to the surgical injury to the first operated knee. In the present study, the investigators will evaluate the effect of old age, surgical stress, pain, and the use of analgesics on the residual gastric volume in elderly patients undergoing staged-bilateral total knee arthroplasty.

Interventions

DIETARY_SUPPLEMENTCarbohydrate drinking

Administration of carbohydrate fluid

Sponsors

Seoul National University Bundang Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to 85 Years

Inclusion criteria

* Patients scheduled for staged bilateral total knee arthroplasty aged 65 to 85 years * American Society of Anesthesiologists physical status classification 1, 2, and 3 * Body mass index \< 35 kg/cm2 * Patients administered carbohydrate-containing fluid 2 hours prior to surgery

Exclusion criteria

* Previous surgery of the upper gastrointestinal tract * Achalasia * Diabetes

Design outcomes

Primary

MeasureTime frameDescription
Gastric volume 1First stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutesGastric volume measured before induction of spinal anesthesia using ultrasound
Gastric volume 2Second stage operative, during the gastric volume measuring at preoperative holding area/ an average of 30 minutesGastric volume measured before induction of spinal anesthesia using ultrasound

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026