Bronchiolitis, Hypophosphatemia
Conditions
Keywords
Hypophosphatemia, Bronchiolitis, Paediatric Intensive Care Unit, Risk Factor
Brief summary
Bronchiolitis is a major public health problem and the leading cause of paediatric intensive care unit admission in infants. Hypophosphatemia is common in adult intensive care units and was associated with an increase of the duration of mechanical ventilation and the length of stay. Our hypothesis is that hypophosphatemia is common in bronchiolitis and could be a marker of severity.
Interventions
BIOLOGICALhypophosphatemia occurrence in infants with severe bronchiolitis admitted in a pediatric intensive care unit
Serum phosphorus level \< 1.55 mmol/L at any time between admission and the 5th day.
Sponsors
Hospices Civils de Lyon
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
7 Days to 3 Months
Healthy volunteers
No
Inclusion criteria
* Age \> 7 days and \< 3 months of life * Admission to the pediatric intensive care unit from 01/11/2016 to 31/03/2020 * With a diagnosis of moderate to severe bronchiolitis according to HAS 2019 criteria
Exclusion criteria
* Renal Failure and tubulopathy * Previous disorder of phospho-calcium balance * Malignant pathology * Lenght of stay less than 24 hours * History of cardiac, aortic or hepatic surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| hypophosphatemia occurrence in severe bronchiolitis in infants admitted in a pediatric intensive care unit | At any time in the first 5th days after Pediatric intensive care admission | A serum phosphorus level\< 1.55mmol/L defines the hypophosphatemia. |
Countries
France
Contacts
Primary ContactFlorent Baudin, Dr
Outcome results
None listed