To Decrease Dentin Hypersensitivity
Conditions
Keywords
dentin hypersensitivity, bonding agent, fluoride varnish
Brief summary
Objectives: The aim of this in vivo randomized clinical trial with split-mouth design was to evaluate the clinical efficacy of one in-office application of a fluoride containing varnish and in office application of a bonding resin in adult patients presenting with dentin hypersensitivity. Materials and Methods: The study cohort consisted of 38 Caucasian outpatients, giving a total of 180 teeth were treated by fluoride varnish (FV) and 160 - by bonding agent (BA). Baseline pain in FV group was slightly higher on both scales (SCHIFF and VAS). Outcome measurements were assessed one or two weeks before product application (enrollment), at baseline at the application days (end of the run-in period: T0a, T0b, T0c), and at 1 week and at 1-2-6 months after first treatment.
Interventions
PROCEDUREApplication of varnish fluoride desensitizing agent on buccal surfaces of exposed dentin
Varnish fluoride is a single dose transparent varnish with 5 % sodium fluoride (22.600 ppm fluoride) and 5 % calcium fluoride. The application was performed according to the manufacturer's instructions. The varnish was applied on a clean and dry surface, then after 10-20 seconds to allow the fluoride varnish to be absorbed, was then dried with air.
PROCEDUREApplication of bonding agent desensitizing agent on buccal surfaces of exposed dentin
Bonding agent is a single dose dual curing universal adhesive and its application was performed according to the manufacturer's instruction for cases with hypersensitive tooth necks. The bonding was applied without etching, on a clean and dry surface. After 10 s any excess material was removed and then light cured for 30 s.
Sponsors
University of Roma La Sapienza
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Intervention model description
A randomized, slit-mouth, double blind clinical trial
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* absence of systemic pathologies (ASA class I); * not pregnant or lactating; * good oral hygiene; * with ≥1 sensitive tooth with exposed dentin on upper or lower dental arches; * contemporary presence of exposed dentin both on the left and right counterpart of upper or lower arch.
Exclusion criteria
* domestic or in-office professional fluoride application and bleaching 6 months before beginning of treatment; * long-term use of anti-inflammatory, analgesic and psychotropic drugs; * eating disorders, systemic conditions that cause or predispose patients to develop dentin hypersensitivity (for example, Gastroesophageal reflux disease); * periodontal surgery and within the previous three months before the study; * orthodontic treatment within the previous three months before the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Level of Pain assessment with the Schiff Sensitivity Scale | All study participants were asked to record the pain intensity score at the baseline, before the application of the desensitizing agents | A score of 0, 1, 2 or 3 was given by the participant. 0 = No subject response to stimulus, 1 = Subject response but will continue, 2 = Subject responds and moves or requests discontinuation, 3 = Painful response to stimulus, discontinuation requested. The lower the score, the lower the hypersensitivity. Air-blast stimulus was used: the response to a jet of cold air was rated by the examiner. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Level of Pain assessment with the Visual Analogue Scale (VAS) | All study participants were asked to record the pain intensity score at the baseline, before the application of the desensitizing agents | The level of pain was evaluated on a visual scale from 0 (no pain) to 10 (maximum pain). The lower the score, the lower the hypersensitivity. Air-blast stimulus was used: the response to a jet of cold air was rated by the examiner. |
Countries
Italy
Outcome results
None listed