COVID-19 And Lingering Symptoms In Primary Care Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04813731

Acronym

CALIP

Enrollment

300

Registered

2021-03-24

Start date

2020-12-12

Completion date

2022-06-30

Last updated

2025-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid19, Symptoms and Signs

Brief summary

The ongoing corona virus disease 2019 (COVID-19) is a viral acute respiratory tract infection caused by server acute respiratory syndrom coronavirus typ 2 (SARS-CoV-2). The signs and symptom of SARS-CoV-2 infection vary and most people with COVID-19 experience illness of mild or moderate severity and recover with symptomatic treatment outside of hospital. Studies have found that some people experience lingering/long-lasting symptoms and only a minority of patients were completely free from COVID-19 related symptoms after two months. About one third still had up to two residual symptoms and 55% had three or more. As far as we know no study on lingering symptoms has been published in patients after a mild or moderate infection managed in primary care settings. The aim of this study is to explore the course of disease over a one year period and describe lingering symptoms and their impact on well-being and daily activities in adult non-hospitalized patients with previous established COVID-19 infection.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Confirmed SARS-CoV-2 infection, either by polymeras chain reaction (PCR), or by antigen testing (if authorized/recommended/used by national/local governments) * Symptoms consistent with mild to moderate COVID-19 * Maximum of 2 weeks since positive SARS-CoV-2 test * Aged 18 years and older * Patient able and willing to comply with monthly phone calls.

Exclusion criteria

* Hospitalisation due to COVID-19

Design outcomes

Primary

Measure	Time frame	Description
Time to full recovery symptoms	through study completion, a maximum of 1 year	Number of weeks until back to normal

Countries

Belgium, Denmark, France, Georgia, Germany, Ireland, Italy, Netherlands, Poland, Romania, Sweden

Outcome results