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Shift Work Health Effects

Effect of Work Shift on the Nurses' Health in the Main Assiut University Hospital

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04813536
Enrollment
108
Registered
2021-03-24
Start date
2021-06-30
Completion date
2022-12-31
Last updated
2021-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shift-work Disorder

Brief summary

To identify the health effects of shift work on nurses in Assuit university hospitals . To estimate effect of shift work on co-morbidities among nurses . To determine the shift work associated risk factors predisposing nurses to poor health outcomes and injuries.

Detailed description

The word 'shiftwork' is commonly used to describe irregular, odd, untraditional working hours, or working hours that are away from day work period. Shiftwork dates back to the late 1800s, as applied to guardians of old kingdoms and in the military services. After the innovation of the light, shift work expanded for nonstop production as in steel factories, iron foundries, and material plants. Approximately one-fourth of the workforce in hospitals works unusual hours (away from the traditional diurnal work period) . Shiftwork has a number of advantages and disadvantages to employers, employees, and their families. The advantages for employers include optimal use of energy, facilities, and other resources through extended capital operating time. The advantages for employees include increased income, more free time for daily activities, and saving time by avoiding traffic rush hours. Shiftwork is associated with both short-term and long-term disadvantages on physical and psychophysiological health. Short-term effects include fatigue and difficulties with sleep. Difficulties with sleep are found to be the most common complaint among shift workers. Sleep disturbances were the main reasons that led shift workers to leave night shiftwork owing to disturbed health habits compared with day workers .Gastrointestinal disorders were reported 2-5 times more commonly among shift workers than daytime workers. These disorders range from minor complaints (e.g., constipation, heart burn, distension, and disturbed appetite) to serious gastrointestinal disorders, which may develop into chronic diseases such as chronic gastritis or peptic ulcers. Shiftwork has been also linked to type 2 diabetes and obesity as sleep deprivation activates the immune system and influences glucose metabolism . An association between shiftwork and cardiovascular diseases (CVDs) has been reported. There is a higher risk for CVD such as hypertension, subclinical atherosclerosis, and ischemic heart disease compared with daytime workers . Different types of cancer have been reported in shift workers including cancers of the breast, colon, and endometrium. Shiftwork system causes circadian rhythm disruption, which is probably carcinogenic to humans. Also, shiftwork causes disruption in both social and domestic lifestyle, which is a major consequence of shiftwork, especially with maternal employment that may have some adverse influences on their young children's cognitive and behavioral outcomes.

Interventions

5ml blood to estimate changes of total leucocytic count, Hemoglobin, eosinophilic, monocyte

OTHERlipid profile

5ml blood to estimate changes of plasma triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and HDL-C

OTHERthe Standard Shiftwork Index questionnaire

1. Biographical information: This includes personal data (e.g., age, sex, marital status, and domestic situations), shift details (e.g., shift start and end times), organization of shiftwork, and general job satisfaction 2. Sleep and fatigue: Measures the effect of shiftwork on perceived sleep quality and quantity and fatigue

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 60 Years

Inclusion criteria

* Active working nurses working in Assiut University Hospitals with minimum exposure to work shift for 1 year . * Had free pre-employment records

Exclusion criteria

* Nurses don't record shift work exposure. * Nurses with less than 1 year exposure to shift work, or don't recorded shift work exposure. * Nurses known to had autoimmune disorder or endocrinal disorder before joining job.

Design outcomes

Primary

MeasureTime frameDescription
complete blood pictureonce baseline at time of the data collection of studytotal leucocytic count
lipid profileonce baseline at time of data collectionplasma triglycerides
Sleep Questionnaireonce baseline at time of data collectionpart of standard shift work index,consists of 11 items and aims to identify sleep habits, as well as the extent to which sleep is depending on which shift has been or is about to be worked. A higher score is associated being associated with higher sleep disturbance

Contacts

Primary ContactMariam R Elkhayat, lecturer
mariam.elkhayat@aun.edu.eg+20 00201003708261
Backup ContactSamar Mohsen, demonstrator
samarmohsen2030@gmail.com

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026