Alzheimer's Dementia, Antibiotics, Dementia, Nursing Homes
Conditions
Brief summary
Pilot study to evaluate the feasibility of a pilot embedded pragmatic cluster randomized controlled trial to reduce the duration of antibiotic therapy and number of antibiotic prescriptions in nursing home residents with AD/ADRD.
Detailed description
The overall objective of the proposed investigation is to assess the feasibility of a pilot embedded pragmatic cluster randomized controlled trial (ePCT) to reduce the duration of antibiotic therapy and number of antibiotic prescriptions among nursing home residents with AD/ADRD. With the support of three independently owned and operated nursing homes that are unaffiliated with an academic medical center, we have developed the multicomponent intervention, eCARE-ID (Electronic Consultation for AD/ADRD Residents Experiencing Infectious Diseases). eCARE-ID consists of three components: 1) Tele-ID video clinical consultation services for nursing home residents; 2) electronic consultation (e-consultation) services for healthcare personnel at participating nursing homes; and 3) Tele-ID video antibiotic stewardship services for healthcare personnel including pharmacists at participating nursing homes.
Interventions
DEVICEeCARE-ID
The intervention, eCARE-ID, consists of: 1) telehealth video clinical consultation services for nursing homes residents; 2) electronic consultation services for healthcare personnel; 3) telehealth video antibiotic stewardship services for healthcare personnel
OTHERStandard of Care
Standard of care will be delivered to the control home.
Sponsors
Advarra
National Institute on Aging (NIA)
Brown University
Yale University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
Two participating nursing homes will be assigned to the intervention. One participating nursing home will serve as a control.
Eligibility
Sex/Gender
ALL
Age
65 Years to 120 Years
Healthy volunteers
No
Inclusion criteria
- residence in a participating nursing home
Exclusion criteria
\- Not willing to consent to the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of antibiotic therapy in nursing home residents | 6 months | The primary outcome will be defined as the duration of antibiotic therapy in nursing home residents with AD/ADRD, measured as the total days of antibiotic therapy per 1000 resident-days among residents with ADRD. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of antibiotic prescriptions in nursing home residents | 6 months | The secondary outcome will be defined as the number of antibiotic prescriptions in nursing home residents with AD/ADRD, defined as the total number of antibiotic prescriptions per 1000 resident-days among residents with AD/ADRD. |
Outcome results
None listed