Cancer, Prehabilitation, Surgery
Conditions
Brief summary
The aim of study is to analyse the feasibility of the use of nutritionnal complements after exercices before surgery for cancer. Body composition, muscle function and muscle mass will be analyse too.
Detailed description
A prospective study will be carried out including adult patients with neoplasia who should benefit in their therapeutic strategy from oncological surgery. About fifty patients will be recruited in the oncology / surgery department at the Saint-Luc University Clinics in Brussels. Patients will be assessed at the initial consultation and after the pre-habilitation period, ie the day before the operation. Dietary monitoring will be carried out in parallel with a physical and respiratory preparation program (prehabilitation) and the intake of protein nutritional supplements in the form of powder to be diluted will be carried out after each exercise session.
Interventions
DIETARY_SUPPLEMENTWhey protein
Patient receive protein supplement in liquid form after each exercice session
Sponsors
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient with operable cancer * patient inform consent * min 18 years old * french or english speaking
Exclusion criteria
* neuromuscular pathology * cardiorespiratory or orthopedic pathology that prevents physical activity * cognitive or psychiatric disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Adhesion rate of the use of nutritionnel complements after exercices before surgery for cancer | 3 weeks | The feasibility of this outcome will be assess by the adhesion rate : (number of protein shots taken) / (number of protein shots prescribed). The adhesion will be validated if\> 75% of the holds are respected. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Muscle function | Once at the inclusion and once the day before surgery (3 weeks) | This variable will be studied by the 6-minutes walk test (meters) |
| Nutritional biological markers | Once at the inclusion | These variables will be studied by: prealbumin (g/L) and albumin (g/L) measures |
| Antropometric markers - height | Once at the inclusion and once the day before surgery (3 weeks) | Height (meters) |
| Body composition (lean and fat mass) | Once at the inclusion and once the day before surgery (3 weeks) | Evaluated by an impedancemetry balance : pourcentage of lean and fat mass |
| Antropometric markers - weight | Once at the inclusion and once the day before surgery (3 weeks) | Weight (kilograms) |
| Antropometric markers - BMI | Once at the inclusion and once the day before surgery (3 weeks) | BMI (kg/m²) :weight and height will be combined to report BMI in kg/m² |
| Muscle strength | Once at the inclusion and once the day before surgery (3 weeks) | This variable will be studied by the hand grip test (kilograms) |
Countries
Belgium
Outcome results
None listed