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Automated Caries Detection Using a 3D Intraoral Scanner. An in Vivo Validation Study.

Assessment of the Difference of Fluoresce of the TRIOS 4 Intraoral Scanner of the Same Surface at In Vivo and In Vitro Conditions

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04812405
Enrollment
58
Registered
2021-03-23
Start date
2020-06-03
Completion date
2021-03-10
Last updated
2021-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Patients

Keywords

caries detection, in vivo, intraoral scanner, ICDAS, histology

Brief summary

This in vivo study with in vitro validation assessed four different algorithms (ALG1-ALG4) implemented in the intraoral scanner system for automated caries detection and classification. 3D scans of the examined teeth were obtained both in vivo and vitro, i.e. before and after tooth extraction, in order to assess any possible differences in the performance of the algorithms at different conditions. The latter could potentially help drawing some conclusions regarding i) the validity of the in vitro studies assessing fluorescence method for caries detection, and ii) the in vivo applicability of in vitro results obtained in the past and the future. Additionally, visual-tactile examination using the ICDAS (ICDAS II) criteria19 was conducted on the same teeth in vivo and histological assessment was used as reference test in vitro.

Interventions

DIAGNOSTIC_TESTTrios4

Examination of occlusal surfaces with 3D scanner and optical criteria

Sponsors

National and Kapodistrian University of Athens
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with permanent molars / premolars, * Sound teeth or with caries lesions on the occlusal surfaces.

Exclusion criteria

* Front teeth / deciduous teeth * Teeth with fillings * Teeth with broken crown * Teeth with extensive lesions on the lateral surfaces.

Design outcomes

Primary

MeasureTime frameDescription
Agreement of In vivo validation with in vitro caries detection1 yearTo assess the difference in vivo and in vitro the fluorescence emitted of the TRIOS FLUO intraoral scanner from occlusal surface from 3rd molar before and after extraction

Countries

Greece

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026